204903 | Anti-Complement 5b-9 Rabbit pAb

204903
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityHostAntibody Type
      H, M Rb Polyclonal Antibody

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      204903-1MG
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      Limited AvailabilityLimited Availability
      Stocked 
      Discontinued
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      Available
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          Plastic ampoule 1 mg
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          Description
          OverviewRecognizes complement component complex Cb5-C9.
          Catalogue Number204903
          Brand Family Calbiochem®
          SynonymsAnti-Terminal Complement Complex, Anti-Membrane Attack Complex, Anti-MAC
          References
          ReferencesSchafer, H., et al. 1986. J. Immunol. 137, 1945.
          Product Information
          FormLiquid
          FormulationIn PBS, pH 7.2.
          Preservative≤0.1% sodium azide
          Applications
          Application ReferencesFrozen Sections Niculescu, F., et al. 2005. Exp. Mol. Pathol. 79, 136.
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          Frozen Sections
          Immunofluorescence
          Paraffin Sections
          Application NotesFrozen Sections (see application references)
          Immunofluorescence (see comments)
          Paraffin Sections (see comments, heat pre-treatment required)
          Radial Immunodiffusion (use undiluted)
          Application CommentsBy immunodiffusion the antibody is monospecific for C5b-9 complex in purified form or present in cobra venom factor activated human serum. There is no reactivity vs. non-activated normal human serum or plasma. Also reported to work for immunofluorescence. This antibody has been shown to work for formalin-fixed paraffin sections; use of citrate buffer and a pressure cooker for 1 min is required for antigen retrieval. Antibody should be titrated for optimal results in individual systems.
          Biological Information
          Immunogenpurified human SC5b-9 complex
          ImmunogenHuman
          HostRabbit
          IsotypeIgG
          Species Reactivity
          • Human
          • Mouse
          Antibody TypePolyclonal Antibody
          Concentration Label Please refer to vial label for lot-specific concentration
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Blue Ice Only
          Toxicity Standard Handling
          Storage -20°C
          Avoid freeze/thaw Avoid freeze/thaw
          Do not freeze Ok to freeze
          Special InstructionsFollowing intial thaw, aliquot and freeze (-20°C).
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          204903

          References

          Reference overview
          Schafer, H., et al. 1986. J. Immunol. 137, 1945.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision11-December-2007 JSW
          SynonymsAnti-Terminal Complement Complex, Anti-Membrane Attack Complex, Anti-MAC
          ApplicationFrozen Sections (see application references)
          Immunofluorescence (see comments)
          Paraffin Sections (see comments, heat pre-treatment required)
          Radial Immunodiffusion (use undiluted)
          DescriptionProtein A purified rabbit polyclonal antibody. Recognizes the C5b-C9 complement component complex.
          BackgroundC5b-9 is the cytolytically active glycoprotein complex, comprised of C5b, C6, C7, C8 and C9 complement proteins, formed as a result of complement activation via either the classical or alternative pathways.
          HostRabbit
          Immunogen speciesHuman
          Immunogenpurified human SC5b-9 complex
          IsotypeIgG
          Specieshuman, mouse
          FormLiquid
          FormulationIn PBS, pH 7.2.
          Concentration Label Please refer to vial label for lot-specific concentration
          Preservative≤0.1% sodium azide
          CommentsBy immunodiffusion the antibody is monospecific for C5b-9 complex in purified form or present in cobra venom factor activated human serum. There is no reactivity vs. non-activated normal human serum or plasma. Also reported to work for immunofluorescence. This antibody has been shown to work for formalin-fixed paraffin sections; use of citrate buffer and a pressure cooker for 1 min is required for antigen retrieval. Antibody should be titrated for optimal results in individual systems.
          Storage -20°C
          Avoid freeze/thaw
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing intial thaw, aliquot and freeze (-20°C).
          Toxicity Standard Handling
          ReferencesSchafer, H., et al. 1986. J. Immunol. 137, 1945.
          Application referencesFrozen Sections Niculescu, F., et al. 2005. Exp. Mol. Pathol. 79, 136.