504394 | AIDA - CAS 168560-79-0 - Calbiochem

504394
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₁H₁₁NO₄ 168560-79-0

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      5.04394.0001
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          Glass bottle 5 mg
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          Description
          OverviewA relatively potent and selective antagonist for group I mGlu receptor subtype 1 (pKB = 3.4 for mGlu1a). Complete absence of interacting with on group II or III mGluRs, or ionotropic glutamate receptors. Widely used in studying neural plasticity, learning and memory, and fear conditioning. Centrally active following systemic administration in vivo.
          Catalogue Number504394
          Brand Family Calbiochem®
          Synonyms(RS)-1-Aminoindan-1,5-dicarboxylic acid, UPF 523
          References
          ReferencesPellicciari, R., et al. 1995. J. Med. Chem. 38, 3717.
          Moroni, F., et al. 1997. J. Pharmacol. Exp. Ther. 281, 721.
          Nielsen, K., et al. 1997. Eur. J. Pharmacol. 326, 105.
          Christoffersen, G., et al. 1999, Neuropharmacology. 38, 817.
          Product Information
          CAS number168560-79-0
          FormOff-white powder
          Hill FormulaC₁₁H₁₁NO₄
          Chemical formulaC₁₁H₁₁NO₄
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetmGlu1a
          Purity≥98% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage +15°C to +30°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          References

          Reference overview
          Pellicciari, R., et al. 1995. J. Med. Chem. 38, 3717.
          Moroni, F., et al. 1997. J. Pharmacol. Exp. Ther. 281, 721.
          Nielsen, K., et al. 1997. Eur. J. Pharmacol. 326, 105.
          Christoffersen, G., et al. 1999, Neuropharmacology. 38, 817.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision28-June-2013 JSW
          Synonyms(RS)-1-Aminoindan-1,5-dicarboxylic acid, UPF 523
          DescriptionAA relatively potent and selective antagonist for group I mGlu receptor subtype 1 (pKB = 3.4 for mGlu1a). Complete absence of interacting with on group II or III mGluRs, or ionotropic glutamate receptors. Widely used in studying neural plasticity, learning and memory, and fear conditioning. Centrally active following systemic administration in vivo.
          FormOff-white powder
          CAS number168560-79-0
          Chemical formulaC₁₁H₁₁NO₄
          Structure formulaStructure formula
          Purity≥98% by HPLC
          SolubilityDMSO (2 mg/ml)
          Storage +15°C to +30°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesPellicciari, R., et al. 1995. J. Med. Chem. 38, 3717.
          Moroni, F., et al. 1997. J. Pharmacol. Exp. Ther. 281, 721.
          Nielsen, K., et al. 1997. Eur. J. Pharmacol. 326, 105.
          Christoffersen, G., et al. 1999, Neuropharmacology. 38, 817.