480354 | 7S NGF, Mouse Submaxillary Glands

480354
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      Overview

      Replacement Information

      Key Specifications Table

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      480354-100UG
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          Plastic ampoule 100 μg
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          Description
          OverviewNative 7S nerve growth factor from mouse submaxillary glands. Promotes neuron survival and neurite outgrowth in newborn rat brain. Composed of three subunits: (α: β: γ): 2:1:2. The α-subunit is an inactive serine proteinase and the γ-subunit is an active serine proteinase capable of processing the precursor form of β-NGF.
          Catalogue Number480354
          Brand Family Calbiochem®
          Synonyms7S Nerve Growth Factor
          References
          ReferencesBax, B., et al. 1997. Structure 5, 1275.
          Shao, N., et al. 1993. Brain Res. 609, 338.
          Varon, S., et al. 1972. Methods Neurochem. 3, 203.
          Product Information
          FormLyophilized
          FormulationLyophilized from sterile H₂O.
          Applications
          Biological Information
          Biological activityED₅₀: Determined by half maximal growth of PC12 cells. Please see vial label for lot-specific ED₅₀.
          Physicochemical Information
          ContaminantsEGF: none detected
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 2 weeks at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          480354

          References

          Reference overview
          Bax, B., et al. 1997. Structure 5, 1275.
          Shao, N., et al. 1993. Brain Res. 609, 338.
          Varon, S., et al. 1972. Methods Neurochem. 3, 203.

          Brochure

          Title
          Growth Factors and Cytokines Technical Bulletin
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision04-January-2010 JSW
          Synonyms7S Nerve Growth Factor
          DescriptionNative 7S nerve growth factor from mouse submaxillary glands. Promotes neuron survival and neurite outgrowth in newborn rat brain. Composed of three subunits (α:β:γ) 2:1:2. The α-subunit is an inactive serine proteinase and the γ-subunit is an active serine proteinase capable of processing the precursor form of β-NGF.
          FormLyophilized
          FormulationLyophilized from sterile H₂O.
          ContaminantsEGF: none detected
          Biological activityED₅₀: Determined by half maximal growth of PC12 cells. Please see vial label for lot-specific ED₅₀.
          SolubilityNeutral (pH 7.0) buffers (1 mg/ml). The 7S NGF complex will dissociate in acidic or basic buffers, so it is critical that the pH of the reconstitution buffer be neutral.
          Storage +2°C to +8°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 2 weeks at -20°C.
          Toxicity Standard Handling
          Merck USA index14, 6477
          ReferencesBax, B., et al. 1997. Structure 5, 1275.
          Shao, N., et al. 1993. Brain Res. 609, 338.
          Varon, S., et al. 1972. Methods Neurochem. 3, 203.

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          Categories

          Life Science Research > Proteins and Enzymes > Cytokines & Growth Factors
          Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors