484100 5-Nitro-2-(3-phenylpropylamino)benzoic Acid - CAS 107254-86-4 - Calbiochem

484100
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₆H₁₆N₂O₄ 107254-86-4

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      484100-10MG
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          Plastic ampoule 10 mg
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          Description
          OverviewPotent Cl channel blocker (IC50 = 100 nM-100 µM), depending on channel subtype and assay method. Inhibits cyclooxygenase (IC50 = 8 µM).
          Catalogue Number484100
          Brand Family Calbiochem®
          SynonymsNPPB, CaCC Blocker II, Calcium-Activated, TMEM16 Blocker II, ANO Blocker II, Anoctamin Blocker II
          References
          ReferencesIllek, B., et al. 1992. Am. J. Physiol. 263, C644.
          Kirk, K., et al. 1992. J. Biol. Chem. 267, 23475.
          Breuer, W., et al. 1989. Biochem. Biophys. Res. Commun. 163, 398.
          Wangermann, P., et al. 1986. Pflugers Arch. 407, S128.
          Product Information
          CAS number107254-86-4
          ATP CompetitiveN
          FormYellow solid
          Hill FormulaC₁₆H₁₆N₂O₄
          Chemical formulaC₁₆H₁₆N₂O₄
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetCl⁻ channel blocker
          Primary Target IC<sub>50</sub>100 nM-100 µM as Cl-channel blocker
          Purity≥98% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +15°C to +30°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          484100

          References

          Reference overview
          Illek, B., et al. 1992. Am. J. Physiol. 263, C644.
          Kirk, K., et al. 1992. J. Biol. Chem. 267, 23475.
          Breuer, W., et al. 1989. Biochem. Biophys. Res. Commun. 163, 398.
          Wangermann, P., et al. 1986. Pflugers Arch. 407, S128.

          Brochure

          Title
          Channel Blockers Technical Bulletin
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision24-April-2015 JSW
          SynonymsNPPB, CaCC Blocker II, Calcium-Activated, TMEM16 Blocker II, ANO Blocker II, Anoctamin Blocker II
          DescriptionPotent Cl- channel blocker (IC50 = 100 nM-100 µM), depending on channel subtype and assay method. Inhibits cyclooxygenase (IC50 = 8 µM).
          FormYellow solid
          CAS number107254-86-4
          Chemical formulaC₁₆H₁₆N₂O₄
          Structure formulaStructure formula
          Purity≥98% by HPLC
          SolubilityDMSO (5 mg/ml) or warm Ethanol
          Storage +15°C to +30°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesIllek, B., et al. 1992. Am. J. Physiol. 263, C644.
          Kirk, K., et al. 1992. J. Biol. Chem. 267, 23475.
          Breuer, W., et al. 1989. Biochem. Biophys. Res. Commun. 163, 398.
          Wangermann, P., et al. 1986. Pflugers Arch. 407, S128.