524394 | 4α-Phorbol-12,13-didecanoate - CAS 27536-56-7 - Calbiochem

524394
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₄₀H₆₄O₈ 27536-56-7

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      524394-1MG
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          Alu drum 1 mg
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          524394-5MG
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              Alu drum 5 mg
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              Description
              OverviewInactive on mouse skin as an inflammatory and tumor-promoting agent. Useful as a negative control for Phorbol-12,13-didecanoate (PDD; Cat. No. 524392) and Phorbol-12-myristate-13-acetate (PMA; Cat. No. 524400).
              Catalogue Number524394
              Brand Family Calbiochem®
              Synonyms4αPDD, PKC Activator I, Negative Control
              References
              ReferencesAkiguchi, I., et al. 1993. Endocrinology 138, 379.
              Clarke, B.L., et al. 1993. Endocrinology 132, 1168.
              Natarajan, V. and Garcia, J.G. 1993. J. Lab. Clin. Med. 121, 337.
              Slomiany, B.L., et al. 1992. J. Physiol. Pharmacol. 43, 223.
              Product Information
              CAS number27536-56-7
              ATP CompetitiveN
              FormSolid
              Hill FormulaC₄₀H₆₄O₈
              Chemical formulaC₄₀H₆₄O₈
              ReversibleN
              Structure formula ImageStructure formula Image
              Applications
              Application4α-Phorbol-12,13-didecanoate, CAS 27536-56-7, is a negative control for phorbol esters PDD (Cat. No. 524392) & PMA (Cat. No. 524400). Inactive on mouse skin as an inflammatory & tumorigenic agent.
              Biological Information
              Primary TargetA negative control for Phorbol-12,13-didecanoate (PDD) and Phorbol-12-myristate-13-acetate (PMA)
              Purity>99% by HPLC
              Physicochemical Information
              Cell permeableN
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              Safety Information
              R PhraseR: 26/27/28-36/37/38

              Very toxic by inhalation, in contact with skin and if swallowed.
              Irritating to eyes, respiratory system and skin.
              S PhraseS: 26-27-36/37/39-45

              In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
              Take off immediately all contaminated clothing.
              Wear suitable protective clothing, gloves and eye/face protection.
              In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Ambient Temperature Only
              Toxicity Highly Toxic
              Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
              Storage -20°C
              Do not freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 6 months at -20°C.
              Packaging Information
              Packaged under inert gas Packaged under inert gas
              Transport Information
              Supplemental Information
              Specifications

              Documentation

              SDS

              Title

              Safety Data Sheet (SDS) 

              Certificates of Analysis

              TitleLot Number
              524394

              References

              Reference overview
              Akiguchi, I., et al. 1993. Endocrinology 138, 379.
              Clarke, B.L., et al. 1993. Endocrinology 132, 1168.
              Natarajan, V. and Garcia, J.G. 1993. J. Lab. Clin. Med. 121, 337.
              Slomiany, B.L., et al. 1992. J. Physiol. Pharmacol. 43, 223.
              Data Sheet

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision20-May-2008 RFH
              Synonyms4αPDD, PKC Activator I, Negative Control
              DescriptionReported to be inactive on mouse skin as an inflammatory and tumor-promoting agent. Used as a negative control for phorbol-12,13-didecanoate (PDD, Cat. No. 524392) and phorbol-12-myristate-13-acetate (PMA, Cat. No. 524400).
              FormSolid
              Intert gas (Yes/No) Packaged under inert gas
              CAS number27536-56-7
              Chemical formulaC₄₀H₆₄O₈
              Structure formulaStructure formula
              Purity>99% by HPLC
              SolubilityDMSO or ethanol
              Storage -20°C
              Do Not Freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 6 months at -20°C.
              Toxicity Highly Toxic
              ReferencesAkiguchi, I., et al. 1993. Endocrinology 138, 379.
              Clarke, B.L., et al. 1993. Endocrinology 132, 1168.
              Natarajan, V. and Garcia, J.G. 1993. J. Lab. Clin. Med. 121, 337.
              Slomiany, B.L., et al. 1992. J. Physiol. Pharmacol. 43, 223.