178221 α₂-Antiplasmin, Human Plasma - Calbiochem

178221
  
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      Overview

      Replacement Information

      Key Specifications Table

      Description
      OverviewA 452-amino acid glycoprotein present in plasma at about 70 µg/ml. Efficiently inhibits the plasminogen activator-induced lysis of fibrin clots. Forms a covalent complex with plasmin and inactivates it.
      Catalogue Number178221
      Brand Family Calbiochem®
      Synonymsα₂-Protease Inhibitor, Primary Plasmin Inhibitor
      References
      ReferencesSchaefer, B.M., et al. 1996. Arch. Dermatol. Res. 288, 122.
      Aoki, N., et al. 1980. Blood 55, 483.
      Saito, H., et al. 1974. Circ. Res. 34, 641.
      Product Information
      Unit of DefinitionOne Inhibitory Unit (I.U.) is defined as the amount of enzyme that will inhibit 1 unit plasmin activity using tosyl-Gly-Pro-Lys-<i>p</i>NA as substrate at 25°C, pH 7.8
      ATP CompetitiveN
      FormSolid
      FormulationLyophilized from 200 mM NaCl, 20 mM Bis-Tris, pH 6.4.
      ReversibleN
      Applications
      Biological Information
      Primary TargetPlasminogen activator-induced lysis of fibrin clots
      Purity≥95% by SDS-PAGE
      SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Specific Activity≥5 I.U./mg protein
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      α₂-Antiplasmin, Human Plasma - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      α₂-Antiplasmin, Human Plasma - Calbiochem Certificates of Analysis

      TitleLot Number
      178221

      References

      Reference overview
      Schaefer, B.M., et al. 1996. Arch. Dermatol. Res. 288, 122.
      Aoki, N., et al. 1980. Blood 55, 483.
      Saito, H., et al. 1974. Circ. Res. 34, 641.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision02-May-2008 JSW
      Synonymsα₂-Protease Inhibitor, Primary Plasmin Inhibitor
      DescriptionA 452-amino acid glycoprotein present in plasma at about 70 µg/ml. Efficiently inhibits the plasminogen-activator-induced lysis of fibrin clots. Forms a covalent complex with plasmin and inactivates it.
      FormSolid
      FormulationLyophilized from 200 mM NaCl, 20 mM Bis-Tris, pH 6.4.
      SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Purity≥95% by SDS-PAGE
      Specific activity≥5 I.U./mg protein
      Unit definitionOne Inhibitory Unit (I.U.) is defined as the amount of enzyme that will inhibit 1 unit plasmin activity using tosyl-Gly-Pro-Lys-pNA as substrate at 25°C, pH 7.8
      SolubilityH₂O. Please refer to the vial label for the lot-specific reconstitution volume.
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesSchaefer, B.M., et al. 1996. Arch. Dermatol. Res. 288, 122.
      Aoki, N., et al. 1980. Blood 55, 483.
      Saito, H., et al. 1974. Circ. Res. 34, 641.