538927 15d-PGJ₂ - CAS 87893-55-8 - Calbiochem

538927
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₂₀H₂₈O₃ 87893-55-8

      Pricing & Availability

      Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
      538927-1MG
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          Plastic ampoule 1 mg
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          Description
          OverviewA metabolite of PGD2 that has recently been identified as a natural ligand for PPARγ-dependent adipogenesis in transfected NIH/3T3 cells and for PPARγ response element (PPRE) in CV-1 cells. Competes with thiazolidinediones for PPARγ binding. Down-regulates inducible nitric oxide synthase (iNOS).
          Catalogue Number538927
          Brand Family Calbiochem®
          SynonymsProstaglandin J₂, 15-Deoxy-Δ12,14, PPAR Agonist VII, PPARγ Agonist VI
          References
          ReferencesPetrova, T.V., et al. 1999. Proc. Natl. Acad. Sci. USA 96, 4668.
          Ricote, M., et al. 1998. Nature 391, 79.
          Forman, B.M., et al. 1995. Cell 83, 803.
          Kliewer, S.A., et al. 1995. Cell 83, 813.
          Product Information
          CAS number87893-55-8
          ATP CompetitiveN
          FormOil
          Hill FormulaC₂₀H₂₈O₃
          Chemical formulaC₂₀H₂₈O₃
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetA natural ligand for PPARγ-dependent adipogenesis
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          R PhraseR: 20/21/22

          Harmful by inhalation, in contact with skin and if swallowed.
          S PhraseS: 36

          Wear suitable protective clothing.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Blue Ice Only
          Toxicity Harmful
          Storage -20°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          15d-PGJ₂ - CAS 87893-55-8 - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          15d-PGJ₂ - CAS 87893-55-8 - Calbiochem Certificates of Analysis

          TitleLot Number
          538927

          References

          Reference overview
          Petrova, T.V., et al. 1999. Proc. Natl. Acad. Sci. USA 96, 4668.
          Ricote, M., et al. 1998. Nature 391, 79.
          Forman, B.M., et al. 1995. Cell 83, 803.
          Kliewer, S.A., et al. 1995. Cell 83, 813.

          Brochure

          Title
          Bioactive Lipids Technical Bulletin
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision15-July-2016 JSW
          SynonymsProstaglandin J₂, 15-Deoxy-Δ12,14, PPAR Agonist VII, PPARγ Agonist VI
          DescriptionA metabolite of PGD2 that has recently been identified as a natural ligand for PPARγ-dependent adipogenesis in transfected 3T3 cells and for PPARγ response element (PPRE) in CV-1 cells. Competes with thiazolidinediones for PPARγ binding.
          FormOil
          Intert gas (Yes/No) Packaged under inert gas
          CAS number87893-55-8
          Chemical formulaC₂₀H₂₈O₃
          Structure formulaStructure formula
          Purity≥95% by HPLC
          SolubilityDMSO (25 mg/ml) or ethanol (25 mg/ml)
          Storage -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Harmful
          ReferencesPetrova, T.V., et al. 1999. Proc. Natl. Acad. Sci. USA 96, 4668.
          Ricote, M., et al. 1998. Nature 391, 79.
          Forman, B.M., et al. 1995. Cell 83, 803.
          Kliewer, S.A., et al. 1995. Cell 83, 813.