505419 α,β-methylene ATP - CAS 104809-20-3 - Calbiochem

505419
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₁H₁₈N₅O₁₂P₃ • xLi+ 104809-20-3

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      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      5.05419.0001
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          Glass bottle 5 mg
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          Description
          OverviewA metabolically stable and selective P2X purinergic receptor agonist (pEC50 = 5.81) that is shown to be more potent than ATP. Elicits contractions in ileum through the release of endogenous acetylcholine, which can be blocked by tetrodotoxin (~1 mM). Shown to depolarize cells of the longitudinal muscle strips (~ 200 nM to 4 µM) that reaches a peak within 2-3 min after application and then decays to a steady level.
          Catalogue Number505419
          Brand Family Calbiochem®
          Synonymsαβ-MeATP, αβ-methylene ATP, P2X purinergic receptor agonist, α,β-methylene ATP, α,β-Methyleneadenosine 5ʹ-triphosphate lithium salt
          References
          ReferencesSawyer, G.W., et al. 2000. Br. J. Pharmacol. 129, 1458.
          Komori, S., et al. 1988. Br. J. Pharmacol. 94, 9.
          Product Information
          CAS number104809-20-3
          FormWhite powder
          Hill FormulaC₁₁H₁₈N₅O₁₂P₃ • xLi+
          Chemical formulaC₁₁H₁₈N₅O₁₂P₃ • xLi+
          Hygroscopic Hygroscopic
          ReversibleY
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetP2X
          Purity≥98% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Sawyer, G.W., et al. 2000. Br. J. Pharmacol. 129, 1458.
          Komori, S., et al. 1988. Br. J. Pharmacol. 94, 9.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision30-August-2013 JSW
          Synonymsαβ-MeATP, αβ-methylene ATP, P2X purinergic receptor agonist, α,β-methylene ATP, α,β-Methyleneadenosine 5ʹ-triphosphate lithium salt
          DescriptionA metabolically stable and selective P2X purinergic receptor agonist (pEC50 = 5.81) that is shown to be more potent than ATP. Elicits contractions in ileum through the release of endogenous acetylcholine, which can be blocked by tetrodotoxin (~1 mM). Shown to depolarize cells of the longitudinal muscle strips (~ 200 nM to 4 µM) that reaches a peak within 2-3 min after application and then decays to a steady level.
          FormWhite powder
          CAS number104809-20-3
          Chemical formulaC₁₁H₁₈N₅O₁₂P₃ • xLi+
          Structure formulaStructure formula
          Purity≥98% by HPLC
          SolubilityH₂O (100 mg/ml)
          Storage -20°C
          Hygroscopic
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesSawyer, G.W., et al. 2000. Br. J. Pharmacol. 129, 1458.
          Komori, S., et al. 1988. Br. J. Pharmacol. 94, 9.