407320 | γ-Interferon, Mouse, Recombinant, E. coli

407320
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      Overview

      Replacement Information

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      407320-100UG
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          Plastic ampoule 100 μg
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          407320-20UG
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              Plastic ampoule 20 μg
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              Description
              OverviewRecombinant, mouse γ-interferon (γ-IFN) expressed in E. coli as a single, non-glycosylated polypeptide containing 134 amino acids. Purified by chromatographic methods. IFN-γ is a type II cytokine produced by activated T cells and natural killer cells. It plays a significant role immunoregulation and has been implicated in the induction of the expression of class II histocompatibility molecules in cells that do not normally express them, resulting in autoimmune disease.
              Catalogue Number407320
              Brand Family Calbiochem®
              SynonymsInterferon γ precursor, IFN-γ, rmIFN-γ
              References
              ReferencesAlvarado, J., et al. 2005. Immunol. Lett. 99, 109.
              Di Rosa, M., et al. 2005. Clin. Chem. Lab. Med. 43, 499.
              Malaguarnera, L., et al. 2005. J. Clin. Lab. Anal. 19, 128.
              Product Information
              FormLyophilized
              FormulationLyophilized from 0.5X PBS, pH 7.2.
              Applications
              Biological Information
              Biological activityReported as IU/mg on a lot-specific basis using a cytopathic effect inhibition assay.
              Purity≥95% by RP-HPLC, FPLC, and SDS-PAGE
              Physicochemical Information
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              Safety Information
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Blue Ice Only
              Toxicity Standard Handling
              Storage -20°C
              Protect from Moisture Protect from moisture
              Do not freeze Ok to freeze
              Special InstructionsFollowing reconstitution, refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for 2-7 days at 4°C or for up to 4 months at -20°C. Avoid freeze/thaw cycles of solutions.
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications

              Documentation

              SDS

              Title

              Safety Data Sheet (SDS) 

              Certificates of Analysis

              TitleLot Number
              407320

              References

              Reference overview
              Alvarado, J., et al. 2005. Immunol. Lett. 99, 109.
              Di Rosa, M., et al. 2005. Clin. Chem. Lab. Med. 43, 499.
              Malaguarnera, L., et al. 2005. J. Clin. Lab. Anal. 19, 128.
              Data Sheet

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision05-March-2009 JSW
              SynonymsInterferon γ precursor, IFN-γ, rmIFN-γ
              DescriptionRecombinant, mouse γ-interferon (γ-IFN) expressed in E. coli as a single, non-glycosylated polypeptide containing 134 amino acids. Purified by chromatographic methods. IFN-γ is a type II cytokine produced by activated T cells and natural killer cells. It plays a significant role immunoregulation and has been implicated in the induction of the expression of class II histocompatibility molecules in cells that do not normally express them, resulting in autoimmune disease.
              FormLyophilized
              FormulationLyophilized from 0.5X PBS, pH 7.2.
              Purity≥95% by RP-HPLC, FPLC, and SDS-PAGE
              Biological activityReported as IU/mg on a lot-specific basis using a cytopathic effect inhibition assay.
              SolubilityReconstitute with sterile water to ≥100 µg/ml, containing 0.1% HSA or BSA. Further dilute with aqueous buffers just prior to use.
              Storage -20°C
              Protect from moisture
              Do Not Freeze Ok to freeze
              Special InstructionsFollowing reconstitution, refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for 2-7 days at 4°C or for up to 4 months at -20°C. Avoid freeze/thaw cycles of solutions.
              Toxicity Standard Handling
              ReferencesAlvarado, J., et al. 2005. Immunol. Lett. 99, 109.
              Di Rosa, M., et al. 2005. Clin. Chem. Lab. Med. 43, 499.
              Malaguarnera, L., et al. 2005. J. Clin. Lab. Anal. 19, 128.