505762 (+/-)-Clopidogrel Hydrogensulfate - CAS 135046-48-9 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Purinergic P2Y12 Receptor Antagonist, (+/-)-Clopidogrel, Plavix

Primary Target: P2Y₁₂
505762
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₆H₁₆ClNO₂S•H₂SO₄ 135046-48-9

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      5.05762.0001
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          		 Glass bottle 5 mg
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          Description
          OverviewA thienopyridine compound that acts as a specific irreversible inhibitor of purinergic P2Y12 receptors. Blocks ADP-induced platelet aggregation and serves as an anti-thrombotic agent. Shown to reduce vascular inflammation and angiotensin II induced-abdominal aortic aneurysm progression. Clopidogrel is a prodrug that requires activation by CYP enzyme system to produce its pharmacologically active metabolite.
          Catalogue Number505762
          Brand Family Calbiochem®
          SynonymsPurinergic P2Y12 Receptor Antagonist, (+/-)-Clopidogrel, Plavix
          References
          ReferencesLiu, O., et al. 2012. PLoS One. 7, e51707.
          Savi, P., et al. 2005. Semin. Thromb. Hemost. 31, 174.
          Product Information
          CAS number135046-48-9
          FormWhite powder
          Hill FormulaC₁₆H₁₆ClNO₂S•H₂SO₄
          Chemical formulaC₁₆H₁₆ClNO₂S•H₂SO₄
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetP2Y₁₂
          Purity≥98% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          (+/-)-Clopidogrel Hydrogensulfate - CAS 135046-48-9 - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Liu, O., et al. 2012. PLoS One. 7, e51707.
          Savi, P., et al. 2005. Semin. Thromb. Hemost. 31, 174.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision30-August-2013 JSW
          SynonymsPurinergic P2Y12 Receptor Antagonist, (+/-)-Clopidogrel, Plavix
          DescriptionA thienopyridine compound that acts as a specific irreversible inhibitor of purinergic P2Y12 receptors. Blocks ADP-induced platelet aggregation and serves as an anti-thrombotic agent. Shown to reduce vascular inflammation and angiotensin II induced-abdominal aortic aneurysm progression. Clopidogrel is a prodrug that requires activation by CYP enzyme system to produce its pharmacologically active metabolite.
          FormWhite powder
          CAS number135046-48-9
          Chemical formulaC₁₆H₁₆ClNO₂S•H₂SO₄
          Structure formulaStructure formula
          Purity≥98% by HPLC
          SolubilityDMSO (25 mg/ml)
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesLiu, O., et al. 2012. PLoS One. 7, e51707.
          Savi, P., et al. 2005. Semin. Thromb. Hemost. 31, 174.