FCMAB171C5 | Milli-Mark™ Anti-CD4 -PECy5 Antibody, clone MT310

Flow Cytometry Analysis:
Representative lot data.
FACS analysis of anti-human CD4-PE/Cy5 stained human lymphocytes. Cells expressing CD4 (right). CD marker expression levels can vary between different blood specimens.
Flow Cytometry Analysis:
Representative lot data.
FACS analysis of anti-human CD4-PE/Cy5
FCMAB171C5
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      Overview

      Offres spéciales

      Tableau de caractéristiques principal

      Espèces réactivesPrincipales applicationsHôteFormatType d'anticorps
      HumainCytométrie en fluxSourisPhycoérythrine/Cy5Anticorps monoclonal
      Description
      Référence FCMAB171C5
      Synonymes T-cell surface antigen T4/Leu-3
      Nom de marque
      • Milli-Mark
      Description Milli-Mark™ Anti-CD4 -PECy5 Antibody, clone MT310
      Informations générales CD4 is a 55 kDa glycoprotein with four immunoglobulin-like external domains, a transmembrane domain and a highly conserved intracellular domain (Leong, 1999). CD4 acts as a coreceptor in MHC class II-restricted antigen-induced T-cell activation. Further, CD4 has a role in the regulation of T-B lymphocyte adhesion in the absence of antigen recognition, and in thymic differentiation (Piatier-Tonneau, 2002). CD4 is expressed on thymocyte subsets, it marks helper/inducer T cells, and it is expressed in 55-65% of mature peripheral T cells. Subpopulations of suppressor or cytotoxic T cells can be identified among CD4-positive T cells. CD4 is also expressed on monocytes/macrophages, Langerhans cells and other dendritic cells. CD4 is not expressed on B cells. Anti-CD4, MT310, was included in the Second International Workshop and Conference on Human Leucocyte Differentiation Antigens, and studies by a number of laboratories confirmed its reactivity with the CD4 antigen (Miedema, 1986).
      Références bibliographiques
      Informations produit
      Format Phycoérythrine/Cy5
      Spécificité Antibody recognizes Human CD4 antigen.
      Contrôle
      • Human Lymphocytes
      Présentation Purified Mouse monoclonal IgG1 kappa conjugated to PE-Cy5 in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2
      Applications
      Application Detect CD4 using this Milli-Mark Anti-CD4 -PECy5 Antibody, clone MT310 validated for use in FC.
      Principales applications
      • Cytométrie en flux
      Informations biologiques
      Clone MT310
      Concentration Please refer to the Certificate of Analysis for the lot-specific concentration.
      Hôte Souris
      Spécificité Antibody recognizes Human CD4 antigen.
      Isotype IgG1κ
      Espèces réactives Humain
      Species Reactivity Note Tested and passed on Human.
      Type d'anticorps Anticorps monoclonal
      Code Entrez Gene
      Méthode de purification Protein A purfied
      Code UniProt
      Informations physico-chimiques
      Dimensions
      Informations sur les matériaux
      Informations toxicologiques
      Informations de sécurité selon le SGH
      Informations sur la sécurité
      Notifications sur l'utilisation du produit
      Assurance Qualité Evaluated by flow cytometry using human lymphocytes.
      Notification sur l'utilisation
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Informations relatives au stockage et à l'expédition
      Conditions de stockage Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
      Informations sur l'emballage
      Taille du matériau 100 tests
      Informations sur le transport
      Information complémentaire
      Caractéristiques

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      Produits associés classés par : Brand Facette

      Catégories

      Life Science Research > Antibodies and Assays > Primary Antibodies