A Portfolio that Enables Innovation

at Merck Millipore

Innovation at Merck
Innovation is the constant driver of growth for Merck Millipore. In 2013, we invested €160 million in R&D to develop ideas that help our customers enable science quickly and efficiently.

More than 60,000 Merck Millipore products are used in research and analytical laboratories, scientific institutes, the pharmaceutical and biotech industries, and in the production of chemical and biotechnological drugs. From a single scientist at a bench to a large-scale production facility, listening to our customers helps us consistently evaluate and optimize our offerings to meet their changing needs.

At Merck Millipore we place a premium on imagination. We promote and reward creativity at all levels and work to ensure that we stay one step ahead of our customers' emerging needs.

Browse some of our innovations:

Direct Detect® System

Direct Detect System
Merck Millipore’s Direct Detect® System is the first mid-infrared biomolecular quantitation system for quick and simplified measurement of total protein levels. It not only allows precise, amino acid sequence-independent analysis, but also requires only minimal sample amounts (2 microliters) with protein concentrations between 0.2 & 0.5 milligrams/milliliter.

Amnis® Brand ImageStream®X Mark II and FlowSight® Imaging Flow Cytometers

Amnis brand ImageStreamX  Mark II and FlowSight imaging flow cytometers
The devices combine the functional insights of microscopy with the speed, statistical power and fluorenscence sensitivity of flow cytometry. This unique combination enables a broad range of applications that would be impossible using either technique alone.

SmartFlare™ RNA Probes

SmartFlare™ RNA Probes
Merck Millipore developed SmartFlare™ RNA probes for the detection of RNA expression in living cells. Only a single incubation step is necessary to obtain this physiologically relevant data in real time. The probes use inert, non-toxic nanoparticles for specific detection of native RNA, eliminating all sample preparation.

Milliflex® Quantum

Milliflex® Quantum
Merck Millipore’s Milliflex® Quantum is an easy-to-use, florescent staining based system for faster microbial detection. The non-destructive staining procedure significantly improves the microbiological process control and product quality control in the pharmaceutical and biopharmaceutical industries, which traditionally takes several days.

EZ-Fit™ Manifold

EZ-Fit™ Manifold
Merck Millipore’s new EZ-Fit™ Manifold works in collaboration with membrane filtration users across industries worldwide, Merck Millipore developed the new and easy-to-use manifold. The unique design prevents biofilm formation because it has a quick-fit connection for assembly and disassembly without tools and all components can be removed for early cleaning and auto cleaning.


Millitrack® compliance e-Solution allows records to be archived in a compliant electronic format. This completely embedded software for water purification systems was developed specifically for pharmaceutical, biotech, and contract lavatories. It is the first water purification e-solution designed to comply with world-wide guidelines on electronic records and electronic signatures.


With the Chromolith® HPLC columns, excellent seperations are possible in a fraction of the time, generally four times faster, as compared to standrad particle packed columns. Chromolith® columns can simplify and speed up food testing and quailty control procedures radically because they are well suited for the analysis of complex samples.

Spectroquant® Move 100

Spectroquant® Move 100
Spectroquant® Move 100, a precise measuring instrument which one can rely on anytime and anywhere. Spectroquant® More 100 enables immediate relsults of water-analysis on-site and is benefical whenever on-site analysis is required. The Spectroquant® Move 100 is portable and allows direct testing independent from the individual environment and enhanced decisinos of water quality can be taken immediately.


Merck Millipore developed Chromabolt®, a family of prepacked and pre-validated chromatography columns. They are designed for pilot and early clinical manufactoring and help our customers to save significantly valuable time abd resources by eliminating laborious manual column packing and cleaning.

Parteck® SLC

Parteck SLC
Parteck® SLC customers can dramatically improve the dissolution rate of their therapeutics.


Merck Millipore’s launched Provantage® GMP production services for speeding up the time to clinic through innovative products and servies. The new services leverages Merck Millipore’s innovatove products with the years of processing expertise to offer customers an innovatove and flexible approach for process development.