MAB5592X | Anti-Nerve Growth Factor Receptor Alexa Fluor488 conjugated Antibody

The figure shows live confocal imaging of intracellular trafficking of p75NTR using ALEXA labelled MLR2 in NSC34 motor neuron cell line.
The figure shows live confocal imaging of intracellular trafficking of p75NTR using ALEXA labelled M
MAB5592X
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      Overview

      Ofertas especiales

      Tabla espec. clave

      Reactividad según especiesAplicaciones claveHospedadorFormatoTipo de anticuerpo
      Rata, Ser humano, RatónInmunocitoquímica, Citometría de flujoRatónAlexaFluor®488Anticuerpo monoclonal
      Descripción
      Número de catálogo MAB5592X
      Marca de familia Chemicon®
      Sinónimos NGFR
      Nombre comercial
      • Chemicon
      Descripción Anti-Nerve Growth Factor Receptor Alexa Fluor488 conjugated Antibody
      Referencias bibliográficas
      Información del producto
      Formato AlexaFluor®488
      Especificidad Nerve Growth Factor Receptor (NGF Receptor p75).
      Presentación Liquid in PBS, with no preservative.
      Aplicaciones
      Aplicación Anti-Nerve Growth Factor Receptor Alexa Fluor488 conjugated Antibody detects level of Nerve Growth Factor Receptor & has been published & validated for use in FC & IC.
      Aplicaciones clave
      • Inmunocitoquímica
      • Citometría de flujo
      Notas de aplicación Immunocytochemistry
      Flow cytometry
      Optimal working dilutions must be determined by end user.
      Información biológica
      Especies inmunógenas Human p75 coupled to an Fc fragment.
      Hospedador Ratón
      Especificidad Nerve Growth Factor Receptor (NGF Receptor p75).
      Isotipo IgG2a
      Reactividad según especies Rata Ser humano Ratón
      Tipo de anticuerpo Anticuerpo monoclonal
      Número de Entrez Gene
      Resumen de Entrez Gene The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.
      Símbolo de gen
      • NT-3
      • NTF3
      • NT3
      • NGF2
      • HDNF
      • MGC129711
      • NGF-2
      Número UniProt
      Resumen UniProt FUNCTION: SwissProt: P20783 # Seems to promotes the survival of visceral and proprioceptive sensory neurons.
      SIZE: 257 amino acids; 29355 Da
      SUBCELLULAR LOCATION: Secreted.
      TISSUE SPECIFICITY: Brain and peripheral tissues.
      SIMILARITY: SwissProt: P20783 ## Belongs to the NGF-beta family.
      Información fisicoquímica
      Dimensiones
      Información de materiales
      Información toxicológica
      Información de seguridad según el GHS
      Información de seguridad
      Declaraciones de uso del producto
      Declaración de uso
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      • Alexa Fluor® is a registered trademark of Molecular Probes, Inc.
      Información de almacenamiento y transporte
      Condiciones de almacenamiento Up to 4 months: 4°C with appropriate antibacterial agent. Long term storage; Conjugate can be stored at -20°C with addition of glycerol (1:1). Avoid repeated freezing and thawing.
      Información sobre embalaje
      Tamaño material 50 µg
      Información de transporte
      Información complementaria
      Especificaciones

      Documentation

      Ficha datos de seguridad (MSDS)

      Idiomas
      English

      Certificados de análisis

      CargoNúmero de lote
      MOUSE ANTI-NERVE GROWTH FACTOR RECEPTOR ALEXA FLUOR#210; 488 CONJUGATED MONOCLONAL ANTIBODY - 2151821 2151821
      MOUSE ANTI-NERVE GROWTH FACTOR RECEPTOR ALEXA FLUOR#210; 488 CONJUGATED MONOCLONAL ANTIBODY - 2270533 2270533
      MOUSE ANTI-NERVE GROWTH FACTOR RECEPTOR ALEXA FLUOR488 CONJUGATED MONOCLONAL ANTIBODY - 2441445 2441445

      Referencias bibliográficas

      Visión general referenciasPub Med ID
      Chronic exposure to nerve growth factor increases acetylcholine and glutamate release from cholinergic neurons of the rat medial septum and diagonal band of Broca via mechanisms mediated by p75NTR.
      Huh, Carey Y L, et al.
      J. Neurosci., 28: 1404-9 (2008) 2008

      18256260
      Characterization and use of the NSC-34 cell line for study of neurotrophin receptor trafficking.
      Matusica, Dusan, et al.
      J. Neurosci. Res., 86: 553-65 (2008) 2008

      17896795
      Primary sensory neuron addition in the adult rat trigeminal ganglion: evidence for neural crest glio-neuronal precursor maturation.
      Lagares, Alfonso, et al.
      J. Neurosci., 27: 7939-53 (2007) 2007

      Mostrar resumen
      17652585
      Functional monoclonal antibodies to p75 neurotrophin receptor raised in knockout mice.
      Rogers, Mary-Louise, et al.
      J. Neurosci. Methods, 158: 109-20 (2006) 2006

      Mostrar resumen
      16828166

      Ficha técnica

      Cargo
      MOUSE ANTI-NERVE GROWTH FACTOR RECEPTOR ALEXA FLUOR® 488 CONJUGATED

      Productos y aplicaciones relacionados

      Alternative Format

       Número de referencia Descripción  
      MAB5592 Anti-Nerve Growth Factor Receptor Antibody, clone MLR2 Precios y disponibilidad

      Categorías

      Life Science Research > Antibodies and Assays > Primary Antibodies