SRI-13K | Sensitive Rat Insulin RIA

SRI-13K
250 tubes  
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      Overview

      Key Spec Table

      Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
      InsulinRRIA125I, Radioactive
      Description
      Catalogue Number SRI-13K
      Description Sensitive Rat Insulin RIA
      Background Information Insulin, a 5.8 kDa hormone is secreted by the islet beta cells in the pancreas. This kit offers sensitive assay for rat/mouse insulin
      References
      Product Information
      Detection method 125I Radioactive
      Specificity Rat Insulin I 100% Rat Insulin II 100% Human Insulin 100% Porcine Insulin 100% Sheep Insulin 100% Hamster Insulin 100% Mouse Insulin 100% Rat C-Peptide Not Detectable Glucagon Not Detectable Somatostatin Not Detectable Pancreatic Polypeptide No
      Performance
      • ED20 = 0.55 ± 0.01 ng/mL
      • ED80 = 0.09 ± 0.01 ng/mL
      • ED50 = 0.22 ± 0.01 ng/mL
      Precision, %
      • Intra-assay: 2.7–5.8
      • Inter-assay: 3.8–10.8
      Applications
      Application This radioimmunoassay (RIA) measures & quantifies Insulin for use in Metabolism & Endocrine research.
      Key Applications
      • Radioimmunoassay
      Application Notes Two-day disequilibrium incubation at 4°C. Sample volume 100 μL serum, plasma, or tissue culture media.
      Biological Information
      Specificity Rat Insulin I 100% Rat Insulin II 100% Human Insulin 100% Porcine Insulin 100% Sheep Insulin 100% Hamster Insulin 100% Mouse Insulin 100% Rat C-Peptide Not Detectable Glucagon Not Detectable Somatostatin Not Detectable Pancreatic Polypeptide No
      Species Reactivity Rat
      Analytes Available
      • Insulin
      Label 125I-Insulin
      Accuracy
      • 88–108%
      Physicochemical Information
      Linearity of Dilution 84–119%
      Standard Curve Range
      • 0.02–1.0 ng/mL
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size 250 tubes
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Protocols

      Title
      Protocol: Sensitive Rat Insulin

      MSDS

      Languages
      English

      References | 35 Available | See All References

      Reference overviewPub Med ID
      Hypoxic Exercise Training Causes Erythrocyte Senescence and Rheological Dysfunction by Depressed Gardos Channel Activity.
      Mao TY, Fu LL, Wang JS
      J Appl Physiol 2011

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      21551009
      Telmisartan reduces neointima volume and pulse wave velocity 8 months after zotarolimus-eluting stent implantation in hypertensive h
      Hong SJ, Choi SC, Ahn CM, Park JH, Kim JS, Lim DS
      Heart (British Cardiac Society) 97 1425-32. Epub 2011 Jun 23. 2011

      21700754
      Differential roles of hyperglycemia and hypoinsulinemia in diabetes induced retinal cell death: evidence for retinal insulin resistance.
      Patrice E Fort,Mandy K Losiewicz,Chad E N Reiter,Ravi S J Singh,Makoto Nakamura,Steven F Abcouwer,Alistair J Barber,Thomas W Gardner
      PloS one 6 2011

      Show Abstract Full Text Article
      22046295
      Prenatal androgen exposure programs metabolic dysfunction in female mice.
      Roland AV, Nunemaker CS, Keller SR, Moenter SM
      J Endocrinol 2010

      Show Abstract
      20713501
      Activity of the histone deacetylase inhibitor FR235222 on Toxoplasma gondii: inhibition of stage conversion of the parasite cyst form and study of new derivative compounds.
      Maubon D, Bougdour A, Wong YS, Brenier-Pinchart MP, Curt A, Hakimi MA, Pelloux H
      Antimicrob Agents Chemother 54 4843-50. Epub 2010 Aug 16. 2010

      Show Abstract
      20713670
      PKA-dependent potentiation of glucose-stimulated insulin secretion by Epac activator 8-pCPT-2'-O-Me-cAMP-AM in human islets of Langerhans.
      Chepurny OG, Kelley GG, Dzhura I, Leech CA, Roe MW, Dzhura E, Li X, Schwede F, Genieser HG, Holz GG
      American journal of physiology. Endocrinology and metabolism 298 E622-33. Epub 2009 Dec 15. 2010

      Show Abstract Full Text Article
      20009023
      Persistent diet-induced obesity in male C57BL/6 mice resulting from temporary obesigenic diets.
      Juen Guo, William Jou, Oksana Gavrilova, Kevin D Hall
      PloS one 4 e5370 2009

      Show Abstract Full Text Article
      19401758
      Assembly of multilayer PSS/PAH membrane on coherent alginate/PLO microcapsule for long-term graft transplantation.
      Andy Leung, Matt Trau, Lars Keld Nielsen
      Journal of biomedical materials research. Part A 88 226-37 2009

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      18286625
      Development of a compartmental model of zinc kinetics in mice.
      Meryl E Wastney, William A House
      The Journal of nutrition 138 2148-55 2008

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      18936212
      Alleviative effects of s-allyl cysteine and s-ethyl cysteine on MCD diet-induced hepatotoxicity in mice.
      Chun-che Lin, Mei-chin Yin, Wen-hu Liu
      Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 46 3401-6 2008

      Show Abstract
      18786595

      Technical Info

      Title
      QUALITY CONTROL RANGES: Ultra Sensitive Human Insulin RIA Kit, Sensitive Rat Insulin RIA Kit