EZMFGF23-43K | Mouse Fibroblast Growth Factor-23 (FGF-23) ELISA Kit, EZMFGF23-43K

Typical Standard Curve for Mouse FGF-23 ELISA
EZMFGF23-43K
96-well plate  
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      Overview

      Key Spec Table

      Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
      FGF-23MELISAFluorescent, Colorimetric
      Description
      Catalogue Number EZMFGF23-43K
      Description Mouse Fibroblast Growth Factor-23 (FGF-23) ELISA Kit, EZMFGF23-43K
      Background Information FGF-23, a phosphate-regulating hormone, plays a critical role in phosphorus homeostasis. The study of FGF-23 is important in understanding the role it plays in such processes as bone remodeling and kidney function. FGF-23 is responsible for the inhibition of renal tubular reabsorption of inorganic phosphorus and, consequently, the regulation of phosphorus homeostasis. FGF-23 mRNA is expressed in the brain, in the thymus at low levels, in dendritic cells, with the highest expression in osteocytes and osteoblasts during phases of active bone remodeling. Because circulating levels of FGF-23 are regulated by vitamin D and phosphorus, normal skeletal and soft tissue development require vitamin D and a functional vitamin D signaling pathway. Diseases resulting from aberrant FGF-23 expression include inherited forms of rickets, certain kidney diseases and phosphorus-related tumors.
      References
      Product Information
      Detection method Fluorescent Colorimetric
      Specificity The antibody pair used in this assay is specific to Mouse FGF-23 and does not significantly cross-react to other FGF molecules/hormones tested.
      Precision, %
      • Inter-assay: < 15%
      • Intra-assay: < 10%
      Applications
      Key Applications
      • ELISA
      Application Notes The Mouse FGF-23 ELISA kit is used for the quantification of Mouse FGF-23 in serum, plasma, and tissue culture samples. One kit is sufficient to measure 38 unknown samples in duplicate, using 20 μL of sample per well.
      Biological Information
      Specificity The antibody pair used in this assay is specific to Mouse FGF-23 and does not significantly cross-react to other FGF molecules/hormones tested.
      Species Reactivity Mouse
      Analytes Available
      • FGF-23
      Accuracy
      • 96%
      Physicochemical Information
      Sensitivity
      • 0.69 pg/mL
      Linearity of Dilution Please contact Technical Service for this information
      Standard Curve Range
      • 0.137 - 100 ng/mL
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size 96-well plate
      Transport Information
      Supplemental Information
      Specifications