EZHPYYT66K | Human PYY (Total) ELISA

EZHPYYT66K
96-well strip plate  
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      Overview

      Key Spec Table

      Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
      PYY (Total)HELISAColorimetric
      Description
      Catalogue Number EZHPYYT66K
      Description Human PYY (Total) ELISA
      Background Information Peptide YY (PYY) is a hormone released by the lower GI tract with circulating levels increasing after meals in direct proportion to the caloric content. It is one of the major physiological signals to reduce appetite and food intake. Other functions of PYY are the inhibition of gastric acid secretion, GI motility and pancreatic enzyme output.
      References
      Product Information
      Detection method Colorimetric
      Specificity Human PYY 3-36 100%~Human PYY 1-36 104%~Human [Leu31,Pro34] PYY 138%~Human [Pro34] PYY 158%~Porcine, Canine, Rat, or Mouse PYY Not Detectable
      Precision, %
      • Plasma: Intra-assay: 0.9% to 5.8%, Inter-assay: 3.7% - 16.5 %
      • Serum: Intra-assay: 1.5% - 2.7%, Inter-assay: 6.1% - 6.9 %
      Applications
      Application This Human PYY (Total) ELISA is used to measure & quantify PYY (Total) levels in Metabolism & Endocrine & Neuroscience research.
      Key Applications
      • ELISA
      Application Notes 3 hour assay using 20 µL sample size ~ Room Temperature
      Biological Information
      Specificity Human PYY 3-36 100%~Human PYY 1-36 104%~Human [Leu31,Pro34] PYY 138%~Human [Pro34] PYY 158%~Porcine, Canine, Rat, or Mouse PYY Not Detectable
      Species Reactivity Human
      Analytes Available
      • PYY (Total)
      Entrez Gene Number
      Gene Symbol
      • PYY-I
      • PYY
      • PYY1
      UniProt Number
      UniProt Summary FUNCTION: SwissProt: P10082 # This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.
      SIZE: 97 amino acids; 11046 Da
      SUBCELLULAR LOCATION: Secreted.
      SIMILARITY: SwissProt: P10082 ## Belongs to the NPY family.
      Accuracy
      • Plasma: 95.9 – 102.5%
      • Serum: 83.3 – 88.9%
      Physicochemical Information
      Sensitivity
      • 1.4 pg/mL
      Linearity of Dilution Plasma: 94 - 99% Serum: 97 - 105%
      Standard Curve Range
      • 10 - 2,000 pg/mL
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size 96-well strip plate
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      MSDS

      Languages
      English

      References

      Reference overviewPub Med ID
      Peptide tyrosine tyrosine levels are increased in patients with urea cycle disorders.
      Sabrina Mitchell,Teresa Welch-Burke,Logan Dumitrescu,Jefferson P Lomenick,Deborah G Murdock,Dana C Crawford,Marshall Summar
      Molecular genetics and metabolism 106 2012

      Show Abstract
      22459207
      Increased meal frequency does not promote greater weight loss in subjects who were prescribed an 8-week equi-energetic energy-restricted diet.
      Jameason D Cameron,Marie-Josée Cyr,Eric Doucet
      The British journal of nutrition 103 2010

      Show Abstract
      19943985
      Peptide YY (PYY) gene polymorphisms in the 3'-untranslated and proximal promoter regions regulate cellular gene expression and PYY secretion and metabolic syndrome traits in vivo.
      Pei-An Betty Shih,Lei Wang,Stephane Chiron,Gen Wen,Caroline Nievergelt,Manjula Mahata,Srikrishna Khandrika,Fangwen Rao,Maple M Fung,Sushil K Mahata,Bruce A Hamilton,Daniel T O'Connor
      The Journal of clinical endocrinology and metabolism 94 2009

      Show Abstract Full Text Article
      19820027
      Increases in peptide Y-Y levels following oat beta-glucan ingestion are dose-dependent in overweight adults.
      EJ Beck, LC Tapsell, MJ Batterham, SM Tosh, XF Huang
      Nutrition research (New York, N.Y.) 29 705-9 2009

      Show Abstract
      19917449

      Technical Info

      Title
      QUALITY CONTROL RANGES - Human PYY (Total) ELISA