EZHFGF23-32K | Human FGF-23 ELISA Kit

EZHFGF23-32K
96-well plate  
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      Overview

      Key Spec Table

      Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
      FGF-23HELISAFluorescent, Colorimetric
      Description
      Catalogue Number EZHFGF23-32K
      Description Human FGF-23 ELISA Kit
      Background Information Studies demonstrate that Fibroblast Growth Hormone-23 plays a critical role as a phosphate-regulating hormone. FGF-23 is responsible for the inhibition of renal tubular reabsorption of inorganic phosphorus and, consequently, the regulation of phosphorus homeostasis. FGF-23 mRNA is expressed in the brain, in the thymus at low levels, in dendritic cells, with the highest expression in osteocytes and osteoblasts during phases of active bone remodeling. Because circulating levels of FGF-23 are regulated by vitamin D and phosphorus, normal skeletal and soft tissue development require vitamin D and a functional vitamin D signaling pathway. Diseases resulting from aberrant FGF-23 expression include inherited forms of rickets, certain kidney diseases and phosphorus-related tumors.
      References
      Product Information
      Detection method Fluorescent Colorimetric
      Specificity The antibody pair used in this assay cross-reacts 0.01% to Human FGF- 21 and 0.01% to FGF-19.

      No significant cross-reactivity has been observed to other human and rat molecules/hormones tested
      Precision, %
      • Inter-assay: < 11%
      • Intra-assay: < 11%
      Applications
      Application This Human FGF-23 ELISA Kit is used to measure & quantify FGF-23 levels in Metabolism & Inflammation & Immunology research.
      Key Applications
      • ELISA
      Application Notes 50µl sample size, 2-Step assay with <4hr incubation time.
      Biological Information
      Specificity The antibody pair used in this assay cross-reacts 0.01% to Human FGF- 21 and 0.01% to FGF-19.

      No significant cross-reactivity has been observed to other human and rat molecules/hormones tested
      Species Reactivity Human
      Analytes Available
      • FGF-23
      Accuracy
      • Spike/Recovery: 76-101%
      Physicochemical Information
      Sensitivity
      • Sensitivity in Tissue Culture/Serum/Plasma*:
        9.9 pg/ml

        *Minimum Detectable Concentrations
      Linearity of Dilution Please contact Technical Service for this information
      Standard Curve Range
      • 9.9 – 2400 pg/mL
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size 96-well plate
      Transport Information
      Supplemental Information
      Specifications