Milli-Q Integral Water Purification System

Experience the quintessence

Related Resources

One water system - two water quality types

Overview

Specifications

Ordering Information

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Milli-Q® Integral System Clear Sorting & Filtering
Catalogue Numbericon Descriptionicon Pack Sizeicon
ZRXQ003WWMilli-Q® Integral 3 Water Purification System1 Show Pricing & Availability
ZRXQ005WWMilli-Q® Integral 5 Water Purification System1 Show Pricing & Availability
ZRXQ010WWMilli-Q® Integral 10 Water Purification System1 Show Pricing & Availability
ZRXQ015WWMilli-Q® Integral 15 Water Purification System1 Show Pricing & Availability

The Milli-Q® Integral is adapted to the region where the system is installed. It includes a power cord with electrical plug required in the area as well as user manual and Quick Reference Guide in the main language(s) of the area.
Please consult your local EMD Millipore representative to find out which Milli-Q® Integral kit is best adapted to your needs.

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Milli-Q® Integral Systems Consumables Clear Sorting & Filtering
Catalogue Numbericon Descriptionicon Pack Sizeicon
PR0G0T0S2Progard® S2 Pretreatment Pack1 Show Pricing & Availability
PR0G0T0S2USProgard® S2 Pretreatment Pack (US)1 Show Pricing & Availability
PR0G0TNP2Progard® NP2 Pretreatment Pack1 Show Pricing & Availability
PR0G0TNP2USProgard® NP2 Pretreatment Pack (US)1 Show Pricing & Availability
QTUM0TEX1Quantum® TEX Polishing Cartridge1 Show Pricing & Availability
QTUM0TIX1Quantum® TIX Polishing Cartridge1 Show Pricing & Availability
ZFA10UVM1Photooxidation UV Lamp A10® TOC Monitor1 Show Pricing & Availability
ZLXUVLP01UV Lamp1 Show Pricing & Availability
ZMQUVLP01Photooxidation UV Lamp1 Show Pricing & Availability

Please note: Use PR0G0T0S2US when ordering in USA, Canada, and Mexico.

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Milli-Q® Integral Systems Accessories Clear Sorting & Filtering
Catalogue Numbericon Descriptionicon Pack Sizeicon
S0FTKIT01PC Connection Kit1 Show Pricing & Availability
TANKASMINAutomatic Sanitization Module (ASM) Elix® and Milli-Q® Systems1 Show Pricing & Availability
TANKPE03030 Liter Polyethylene Storage Tank1 Show Pricing & Availability
TANKPE06060 Liter Polyethylene Storage Tank1 Show Pricing & Availability
TANKPE100100 Liter Polyethylene Storage Tank1 Show Pricing & Availability
WMBQP0D01Wall Mounting Bracket for Q-POD® and E-POD®1 Show Pricing & Availability
WMBSMT002Wall Mounting Bracket for Milli-Q® systems1 Show Pricing & Availability
ZFWATDET4Water Detector1 Show Pricing & Availability
ZMQSFTS01Foot Pedal Accessory1 Show Pricing & Availability
ZMQSP0D01Q-POD® Ultrapure Water Remote Dispenser1 Show Pricing & Availability
ZRXSP0D01E-POD® Pure Water Remote Dispenser1 Show Pricing & Availability

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Consumables for Milli-Q® Integral Systems Accessories Clear Sorting & Filtering
Catalogue Numbericon Descriptionicon Pack Sizeicon
CDUFBI001Biopak® Ultrafiltration Cartridge1 Show Pricing & Availability
EDSPAK001EDS-Pak® Cartridge1 Show Pricing & Availability
LCPAK0001LC-Pak® Cartridge1 Show Pricing & Availability
MPGL04GK2Millipak® 40 Final Filter2 Show Pricing & Availability
MPGP04001Millipak® 40 Express Final Filter1 Show Pricing & Availability
TANKMPK01Vent Filter for PE Tank (Type 2 Water)1 Show Pricing & Availability
V0CPAK001VOC-Pak® Cartridge1 Show Pricing & Availability
ZLXUVLPL1UV Lamp1 Show Pricing & Availability

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    Documentation

    Brochure

    Title
    Milli-Q® Integral Water Purification Systems

    Technical Info

    Title
    Blank Optimization Using Ultrapure Water Suitable for Trace Ion Analysis.
    High Purity Water for Inorganic Analysis
    Milli-Q Biocel System,Optimized Ultrapure Water Quality for PCR
    Milli-Q Element System Water Quality Assessment
    Nerve Cell Culture via Pyrogen-free Water: Pyrogen Removal of the Milli-Q PF Water System
    Total Organic Carbon in High-Purity Water
    UV Oxidation in Water Purification
    Ultrapure Water for Elemental Analysis down to ppt levels

    References | 97 Available | See All References

    Reference overviewApplicationPub Med ID
    The importance of ultrapure water for nano LC-MS applications
    M. Tarun, S. Mabic, D. Budac, M. Hayward
    The Column (2011) 9 May, Issue 8, 12-17 2011

    Show Abstract Full Text Article
    Quantification of 2-hydrazinopyridine derivatized steroid hormones in fathead minnow (Pimephales promelas) blood plasma using LC-ESI+/MS/MS
    D. Hala, M.D. Overturf, L.H. Petersen, D.B. Huggett
    J. Chromatogr. B 879 591–598 2011

    Show Abstract
    Polishing Up On Water Quality
    C. Devaux, C. Monferran, M. Tarun, E. Riche, D. Darbouret
    Laboratory Equipment – Chromatography Techniques (2010) Dec. 2010

    Show Abstract Full Text Article
    Endotoxin-Free Water for Tissue Culture
    E. Riché, J. Bôle and S. Mabic
    Lab Manager Magazine (2010) May 2010

    Show Abstract Full Text Article
    Determining What's in Your Laboratory Water - "Emerging Contaminants" from the Tap Pose Subtle Threat to Experimental Data
    E. Riché, M. Tarun
    GEN (2010), 30(12) 2010

    Show Abstract Full Text Article
    Designing a customized lab water system
    J. Denoncourt
    Laboratory Design newsletter (2010) 15 (10) 2010

    Show Abstract Full Text Article
    Improving chromatographic performance by using freshly delivered ultrapure water in the mobile phase
    Vivek Joshi, PhD, Senior Scientist, Bioscience Business Unit and Estelle Riche, Senior Scientist, Lab Water Business Field, Merck Millipore
    LCGC "The Peak" (2009), June, 7 - 14 2009

    Show Abstract Full Text Article
    Trace Analysis of Perchlorate: Analytical Method and Removal Efficiency of Purification Technologies
    E. Castillo, E. Riché, I. Kano and S. Mabic
    LCGC "The Peak" (2008) August, 21-30. 2008

    Show Abstract Full Text Article
    Assessment of the acute toxicity of triclosan and methyl triclosan in wastewater based on the bioluminescence inhibition of Vibrio fischeri
    M. Farré, D. Asperger, L. Kantiani, S. González, M. Petrovic, D. Barceló
    Anal Bioanal Chem 390 1999–2007 2008

    Show Abstract
    Extraction of extracellular polymeric substances from extreme acidic microbial biofilms
    A. Aguilera, V. Souza-Egipsy, P. San Martín-Úriz, R. Amils
    Appl Microbiol Biotechnol 78 1079–1088 2008

    Show Abstract

    C72876Experience the quintessence

    The right water quality for all lab activities. The Milli-Q Integral system includes a comprehensive and optimized sequence of water purification and monitoring technologies in a single unit, allowing both pure and ultrapure water to be produced directly from tap.

    It provides pressurized, bacteria-free water through E-POD (Elix-Point-of-Delivery) units and Milli-Q ultrapure water through Q-POD (Quality-Point-of-Delivery) units.

    Water can be delivered from the system’s exclusive production unit to as many as 3 independent PODs that can be conveniently located at different places in the laboratory. Each POD incorporates a color backlit screen enabling the user to check the operation of the entire system and the water quality at a glance.

    The ergonomic design of the PODs accounts for the height and shape of regular laboratory glassware to ensure optimum user convenience.

    Water can be delivered at different flow rates from the mobile dispenser located at the end of an 80 cm recirculation loop. The user can also select a specific water volume and have the Q-POD/E-POD unit automatically fill any laboratory vessel from a 100 mL Erlenmeyer flask to a 5 L calibrated flask or 20 L carboy.

    To ensure easy adaptation to various laboratory applications, validated POD Packs polishers are available to remove contaminants that can impact specific applications (such as pyrogens, nucleases, bacteria, particulates, organics, etc.) just before water leaves the system. Configurations can easily evolve to match lab activity changes or extensions.

    Features

    • Pure and ultrapure water is available directly from tap water (no need to have a DI source in the lab) from 60 L/day up to 350 L/day (depending on model)
    • Consistent production of superior quality pure water (better than twice the quality of distilled water) without the need to regenerate a DI tank, thanks to patented Elix technology
    • Easy pure or ultrapure water delivery in different lab locations thanks to the PODs
    • Easy and intuitive operation
    • Application-specific water qualities through customized final polishers
    • Built-in resistivity and TOC monitors designed to comply with the most demanding norms, including USP requirements (§ 643 and § 645).
    • System manager-specific interface with protection of key set points by a login and password.

    Applications

    When the system is equipped with a 0.2 μm filter, the high purity water delivered by the system is suitable for HPLC, LC-MS, MALDI-ToF-MS, IC, ICP, AA and most of the analytical techniques commonly used in the laboratory. When an ultrafiltration cartridge (BioPak) is utilized at the point-of-use, the water is suitable for genomics applications (quality at least equivalent to DEPC-treated water) and cell culture. The water produced following the system’s pretreatment step may be used for basic laboratory needs, such as buffer and reagent preparation, microbiology media preparation, histology, dissolution testing (with UV detection) and rinsing of glassware.

    The Milli-Q Integral system is designed to be fed by potable tap water as described in US-EPA, EP and WHO norms.

    Elix water (at Elix module outlet)
    Parameter Value
    Resistivity, MΩ•cm @ 25 °C > 5
    TOC, ppb (μg/l) < 30
    Parameter Value
    Bacteria, cfu/ml < 0.1 *
    Particulates > 0.22 μm, Particulates/ml < 1 *
    Pyrogens (endotoxins), EU/ml < 0.001 **
    RNases, ng/ml < 0.01 **
    DNases, pg/μl < 4 **
    (*) With Millipak Express 0.22 µm or Biopak end filter
    (**) With Biopak end filter

    The Milli-Q Integral system is designed to produce ultrapure water in agreement with the quantitative specifications of Type I water as described in ISO 3696, ASTM D1193, and of EP and USP Purified Water, as well as the CLSI® - CLRW.
    Milli-Q® water (sourced from a Q-POD unit)
    Parameter Value
    Resistivity, MΩ•cm @ 25 °C 18.2
    TOC, ppb (μg/l) < 5
    Bacteria, cfu/ml < 0.1 *
    Particulates > 0.22 μm, Particulates/ml < 1 *
    Pyrogens (endotoxins), EU/ml < 0.001 **
    RNases, ng/ml < 0.01 **
    DNases, pg/μl < 4 **
    (*) With Millipak Express 0.22 µm or Biopak end filter
    (**) With Biopak end filter

    Resistivity, TOC and bacteria levels match the requirements of Type II water as described in ISO® 3696, ASTM D1193 (Type II resistivity, TOC, HBC Table 1 specification), and Purified Water as described in USP, EP.