426102 Sigma-Aldrichclasto-Lactacystin β-Lactone - CAS 154226-60-5 - Calbiochem
clasto-Lactacystin β-Lactone, CAS 154226-60-5, is a cell-permeable, highly specific, irreversible 20S proteasome inhibitor.
More>> clasto-Lactacystin β-Lactone, CAS 154226-60-5, is a cell-permeable, highly specific, irreversible 20S proteasome inhibitor. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: Omuralide, Proteasome Inhibitor IX
Overview
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Key Specifications Table
Empirical Formula | CAS # |
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C₁₀H₁₅NO₄ | 154226-60-5 |
Pricing & Availability
Catalog Number | Availability | Packaging | Qty/Pack | Price | Quantity | |
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426102-100UG |
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Plastic ampoule | 100 μg |
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Description | |
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Overview | A highly specific, cell-permeable, and irreversible 20S proteasome inhibitor. It is believed that in vitro, the natural product Lactacystin (Cat. No. 426100) acts as a precursor for clasto-lactacystin β-lactone and that the latter is the sole species that interacts with the proteasome. |
Catalogue Number | 426102 |
Brand Family | Calbiochem® |
Synonyms | Omuralide, Proteasome Inhibitor IX |
Product Information | |
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CAS number | 154226-60-5 |
ATP Competitive | N |
Form | White solid |
Hill Formula | C₁₀H₁₅NO₄ |
Chemical formula | C₁₀H₁₅NO₄ |
Reversible | N |
Structure formula Image |
Applications | |
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Application | clasto-Lactacystin β-Lactone, CAS 154226-60-5, is a cell-permeable, highly specific, irreversible 20S proteasome inhibitor. |
Biological Information | |
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Primary Target | 20S proteasome |
Physicochemical Information | |
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Cell permeable | Y |
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Safety Information according to GHS |
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Supplemental Information |
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Specifications |
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Documentation
SDS
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Certificates of Analysis
Title | Lot Number |
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426102 |
References
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Corey, E.J., and Wei-Dong, Z. 1999. Chem. Pharm. Bull. 47, 1. Dick, L.R., et al. 1997. J. Biol. Chem. 272, 182. Dick, L.R., et al. 1996. J. Biol. Chem. 271, 7273. Fenteany, G., et al. 1995. Science 268, 726. |
Brochure
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Proteasomes Technical Bulletin |
Citations
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