108386 Tris(hydroxymethyl)aminomethane

108386
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      Overview

      Replacement Information

      Key Specifications Table

      CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
      77-86-1 201-064-4 C₄H₁₁NO₃ H₂NC(CH₂OH)₃ 121.14 g/mol Ph Eur,BP,JPC,USP

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      1083860003
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          Fibre case 3 x1 kg
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          1.08386.1000
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              Plastic bottle 1 kg
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              1083865000
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                  Plastic bottle 5 kg
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                  1083869025
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                      Plastic drum 25 kg
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                      Description
                      Catalogue Number108386
                      SynonymsTrometamol, Aminomethylidine trimethanol, 2-Amino-2-hydroxymethyl-1.3-propanediol, TRIS-buffer
                      DescriptionTris(hydroxymethyl)aminomethane
                      References
                      Product Information
                      CAS number77-86-1
                      EC number201-064-4
                      GradePh Eur,BP,JPC,USP
                      Hill FormulaC₄H₁₁NO₃
                      Chemical formulaH₂NC(CH₂OH)₃
                      Molar Mass121.14 g/mol
                      HS Code2922 19 00
                      Structure formula ImageStructure formula Image
                      Applications
                      Biological Information
                      Physicochemical Information
                      Boiling point219 - 220 °C (13.3 hPa)
                      Density1.35 g/cm3 (23 °C)
                      Melting Point171 - 172 °C
                      pH value10.2 - 10.6 (6 g/l, H₂O, 20 °C)
                      Vapor pressure0.0267 hPa (20 °C)
                      Bulk density840 kg/m3
                      Solubility678 g/l
                      Dimensions
                      Materials Information
                      Toxicological Information
                      LD 50 oralLD50 Rat > 5000 mg/kg
                      LD 50 dermalLD50 Rat > 5000 mg/kg
                      Safety Information according to GHS
                      RTECSTY2900000
                      Storage class10 - 13 Other liquids and solids
                      WGKWGK 1 slightly hazardous to water
                      Disposal3
                      Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
                      Safety Information
                      Product Usage Statements
                      Storage and Shipping Information
                      StorageStorage temperature: no restrictions.
                      Packaging Information
                      Transport Information
                      Supplemental Information
                      Specifications

                      Documentation

                      Material Qualification Dossier

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                      Quality Management Dossier

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                      Operational Excellence Dossier

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                      Tris(hydroxymethyl)aminomethane SDS

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                      Safety Data Sheet (SDS) 

                      Tris(hydroxymethyl)aminomethane Certificates of Analysis

                      Product Number PackagingSpecificationLot Number
                      1083860003 Fibre casePDF Specification Document
                      1.08386.1000 Plastic bottlePDF Specification Document
                      1083865000 Plastic bottlePDF Specification Document
                      1083869025 Plastic drumPDF Specification Document

                      Certificates

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                      Categories

                      Small Molecule Pharmaceuticals > Formulation > Liquid Dosage Form > pH Adjustments and Isotonizers
                      Small Molecule Pharmaceuticals > Formulation > Semisolid Dosage Form > Acidulants and pH Adjustments
                      Biopharmaceutical Manufacturing > Downstream Processing > Chromatography > Process Chemicals > Buffers
                      Biopharmaceutical Manufacturing > Formulation > Liquid Dosage > pH Adjustments and Isotonizers