605195 Thrombin, Human Plasma, High Activity

605195
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      Overview

      Replacement Information

      Key Specifications Table

      Pricing & Availability

      Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
      605195-1000U
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          Plastic ampoule 1000 u
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          605195-100U
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              Glass bottle 100 u
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              605195-5000U
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                  Plastic ampoule 5000 u
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                  Description
                  OverviewDesigned for use in thrombin clotting time tests. Key enzyme that activates factor XIII and converts fibrinogen into fibrin.
                  Catalogue Number605195
                  Brand Family Calbiochem®
                  References
                  ReferencesForsberg, G., et al. 1992. J. Protein Chem. 11, 201.
                  Garcia, J.G. 1992. J. Lab. Clin. Med. 120, 513.
                  Scarborough, R.M., et al. 1992. J. Biol. Chem. 267, 13146.
                  Weigel, L.M., et al. 1992. Infect. Immun. 60, 1568.
                  Product Information
                  CAS number9002-04-4
                  Unit of DefinitionOne unit is determined by comparison with a standard curve prepared using the Bureau of Biologics standard thrombin.
                  FormLyophilized solid
                  FormulationLyophilized from 200 mM NaCl, 50 mM sodium citrate, 0.1% PEG-8000, pH 6.5.
                  Quality LevelMQ100
                  Applications
                  Biological Information
                  PurityComplete activation from homogeneous prothrombin by SDS-PAGE
                  SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
                  Specific Activity≥2800 NIH units/mg protein
                  Physicochemical Information
                  Dimensions
                  Materials Information
                  Toxicological Information
                  Safety Information according to GHS
                  RTECSXO8950000
                  Safety Information
                  R PhraseR: 20/21/22

                  Harmful by inhalation, in contact with skin and if swallowed.
                  S PhraseS: 36

                  Wear suitable protective clothing.
                  Product Usage Statements
                  Storage and Shipping Information
                  Ship Code Blue Ice Only
                  Toxicity Harmful
                  Storage -20°C
                  Do not freeze Ok to freeze
                  Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
                  Packaging Information
                  Transport Information
                  Supplemental Information
                  Specifications

                  Documentation

                  Thrombin, Human Plasma, High Activity SDS

                  Title

                  Safety Data Sheet (SDS) 

                  Thrombin, Human Plasma, High Activity Certificates of Analysis

                  TitleLot Number
                  605195

                  References

                  Reference overview
                  Forsberg, G., et al. 1992. J. Protein Chem. 11, 201.
                  Garcia, J.G. 1992. J. Lab. Clin. Med. 120, 513.
                  Scarborough, R.M., et al. 1992. J. Biol. Chem. 267, 13146.
                  Weigel, L.M., et al. 1992. Infect. Immun. 60, 1568.
                  Data Sheet

                  Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

                  Revision19-May-2008 RFH
                  DescriptionDesigned for use in thrombin clotting time tests. Serine protease formed in the plasma during the clotting process from prothrombin, calcium, and thromboplasmin. Acts on the soluble plasma protein fibrinogen to convert it to an insoluble fibrin clot. Prepared from homogenous human prothrombin by activation with Factor Xa, Factor Va, and phospholipid. Designed for use in thrombin time tests.
                  FormLyophilized solid
                  FormulationLyophilized from 200 mM NaCl, 50 mM sodium citrate, 0.1% PEG-8000, pH 6.5.
                  SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
                  CAS number9002-04-4
                  RTECSXO8950000
                  PurityComplete activation from homogeneous prothrombin by SDS-PAGE
                  Specific activity≥2800 NIH units/mg protein
                  Unit definitionOne unit is determined by comparison with a standard curve prepared using the Bureau of Biologics standard thrombin.
                  SolubilityH₂O (1 mg/ml). Solution will have a cloudy appearance.
                  Storage -20°C
                  Do Not Freeze Ok to freeze
                  Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
                  Toxicity Harmful
                  Merck USA index14, 9383
                  ReferencesForsberg, G., et al. 1992. J. Protein Chem. 11, 201.
                  Garcia, J.G. 1992. J. Lab. Clin. Med. 120, 513.
                  Scarborough, R.M., et al. 1992. J. Biol. Chem. 267, 13146.
                  Weigel, L.M., et al. 1992. Infect. Immun. 60, 1568.

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                  Categories

                  Life Science Research > Proteins and Enzymes > Other Enzymes