572201 Streptozotocin - CAS 18883-66-4 - Calbiochem

572201
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₈H₁₅N₃O₇ 18883-66-4

      Pricing & Availability

      Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
      572201-1GM
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          Plastic ampoule 1 gm
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          572201-250MG
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              Plastic ampoule 250 mg
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              Description
              OverviewAn N-nitroso-containing diabetogenic compound that acts as a nitric oxide donor in pancreatic islets. An antibiotic effective against Gram-negative bacteria. Causes DNA alkylation and DNA strand breaks in pancreatic islet cells.
              Catalogue Number572201
              Brand Family Calbiochem®
              Synonyms2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose
              References
              ReferencesKroncke, K.D., et al. 1995. Biol. Chem. Hoppe Seyler 376, 179.
              Kwon, N.S., et al. 1994. FASEB J. 8, 529.
              Rasschaert, J., et al. 1992. Endocrinology 130, 3522.
              Bennett, R.A. and Pegg, A.E. 1981. Cancer Res. 41, 2786.
              Yamamoto, H., et al. 1981. Nature 294, 284.
              Product Information
              CAS number18883-66-4
              FormOff-white to pale yellow crystalline solid
              Hill FormulaC₈H₁₅N₃O₇
              Chemical formulaC₈H₁₅N₃O₇
              Structure formula ImageStructure formula Image
              Applications
              Biological Information
              Purity≥95% by HPLC
              Physicochemical Information
              ContaminantsHeavy metals: ≤5 ppm
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              RTECSLZ5775000
              Safety Information
              R PhraseR: 20/21/22-45-46-61

              Harmful by inhalation, in contact with skin and if swallowed.
              May cause cancer.
              May cause heritable genetic damage.
              May cause harm to the unborn child.
              S PhraseS: 22-36/37/39-45

              Do not breathe dust.
              Wear suitable protective clothing, gloves and eye/face protection.
              In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Ambient Temperature Only
              Toxicity Harmful & Carcinogenic / Teratogenic
              Storage -20°C
              Do not freeze Ok to freeze
              Special InstructionsUnstable in solution; reconstitute just prior to use. Following initial thaw, aliquot and freeze (-20°C).
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications

              Documentation

              Streptozotocin - CAS 18883-66-4 - Calbiochem SDS

              Title

              Safety Data Sheet (SDS) 

              Streptozotocin - CAS 18883-66-4 - Calbiochem Certificates of Analysis

              TitleLot Number
              572201

              References

              Reference overview
              Kroncke, K.D., et al. 1995. Biol. Chem. Hoppe Seyler 376, 179.
              Kwon, N.S., et al. 1994. FASEB J. 8, 529.
              Rasschaert, J., et al. 1992. Endocrinology 130, 3522.
              Bennett, R.A. and Pegg, A.E. 1981. Cancer Res. 41, 2786.
              Yamamoto, H., et al. 1981. Nature 294, 284.

              Brochure

              Title
              Antibiotics Profiler
              Nitric Oxide Donors and Scavengers Technical Bulletin
              Data Sheet

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision24-September-2010 JSW
              Synonyms2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose
              DescriptionAn N-nitroso-containing compound that acts as a nitric oxide donor in pancreatic islets. An antibiotic effective against gram-negative bacteria. Causes DNA alkylation and DNA strand breaks in pancreatic islet cells. A diabetogenic agent.
              FormOff-white to pale yellow crystalline solid
              CAS number18883-66-4
              RTECSLZ5775000
              Chemical formulaC₈H₁₅N₃O₇
              Structure formulaStructure formula
              Purity≥95% by HPLC
              ContaminantsHeavy metals: ≤5 ppm
              SolubilityH₂O
              Storage -20°C
              Do Not Freeze Ok to freeze
              Special InstructionsUnstable in solution; reconstitute just prior to use. Following initial thaw, aliquot and freeze (-20°C).
              Toxicity Harmful & Carcinogenic / Teratogenic
              Merck USA index14, 8832
              ReferencesKroncke, K.D., et al. 1995. Biol. Chem. Hoppe Seyler 376, 179.
              Kwon, N.S., et al. 1994. FASEB J. 8, 529.
              Rasschaert, J., et al. 1992. Endocrinology 130, 3522.
              Bennett, R.A. and Pegg, A.E. 1981. Cancer Res. 41, 2786.
              Yamamoto, H., et al. 1981. Nature 294, 284.