SCM075 ROCK Inhibitor (Y-27632)

SCM075
5 mg  
Retrieving price...
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited AvailabilityLimited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

       

      Contact Customer Service

      Click To Print This Page

      Overview

      Replacement Information

      Key Specifications Table

      Key Applications
      CULT, Neuroscience
      Description
      Catalogue NumberSCM075
      DescriptionROCK Inhibitor (Y-27632)
      Background InformationROCK Inhibitor (Y-27632) is a selective, ATP-competitive inhibitor of Rho-associated protein kinase (ROCK) including p160Rock (Ki=140nM) and Rock-II. Also acts as a potent inhibitor of agonist-induced Ca2+ sensitization of myosin phosphorylation and smooth muscle contraction. One-hour treatment with 10uM Y-27632 blocks apoptosis of dissociated cultured human embryonic stem cells (hESCs), increases survival and cloning efficiency of hESCs without affecting their pluripotency1. Recently, some reports showed that the application of Y-27632 and Accutase (Cat. No. SCR005), a formulated mixture of digestive enzymes, enhances the post-thaw survival rate of single hESCs using conventional slow freezing and rapid thawing methods
      References
      Product Information
      Applications
      ApplicationThe ROCK Inhibitor (Y-27632) is available in a 5 mg format & has been optimized & validated for cell culture & Neuroscience applications.
      Key Applications
      • Cell Culture
      • Neuroscience
      Biological Information
      Media FormLiquid
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsBefore Reconstitution: Maintain at -20ºC, protected from light for 2 years. After Reconstitution: 1 year at -20ºC, protected from light
      Packaging Information
      Material Size5 mg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      ROCK Inhibitor (Y-27632) 5 mg2934776
      ROCK Inhibitor (Y-27632) 5 mg2975574
      ROCK Inhibitor (Y-27632) 5 mg2829752
      ROCK Inhibitor (Y-27632) 5 mg3091588
      ROCK Inhibitor (Y-27632) 5 mg - 24275072427507
      ROCK Inhibitor (Y-27632) 5 mg - 20530292053029
      ROCK Inhibitor (Y-27632) 5 mg - 21960692196069
      ROCK Inhibitor (Y-27632) 5 mg - 23257262325726
      ROCK Inhibitor (Y-27632) 5 mg - NG1946963NG1946963
      ROCK Inhibitor (Y-27632) 5 mg - NRG1734711NRG1734711

      Brochure

      Title
      Human Stem Cell Systems

      Related Products & Applications

      Accessories

      Catalog Number Description  
      NS230 Neurite Outgrowth Assay Plus Kit (3 µm) Show Pricing & Availability
      SCM020 HEScGRO Medium for Human ES Cell Culture Show Pricing & Availability
      SCM020-100 HEScGRO Medium for Human ES Cell Culture Show Pricing & Availability
      SCM021 HEScGRO Basal Medium for Human ES Cell Culture Show Pricing & Availability
      SCM032 Xeno-FREEze™ Human Embryonic Stem (hES) Cell Freezing Medium Show Pricing & Availability
      SCR005 Accutase cell detachment solution Show Pricing & Availability
      SCR006 Accumax cell detachment solution Show Pricing & Availability
      SCR502 Human, iPS Selection Kit Show Pricing & Availability
      SCR530 STEMCCA Constitutive Polycistronic (OKSM) Lentivirus Reprogramming Kit Show Pricing & Availability
      SCR531 STEMCCA Cre-Excisable Constitutive Polycistronic (OKSM) Lentivirus Reprogramming Kit Show Pricing & Availability

      Categories

      Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Media Supplements