SCM075 ROCK Inhibitor (Y-27632)

5 mg  
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      Replacement Information

      Key Specifications Table

      Key Applications
      CULT, Neuroscience
      Catalogue NumberSCM075
      DescriptionROCK Inhibitor (Y-27632)
      Background InformationROCK Inhibitor (Y-27632) is a selective, ATP-competitive inhibitor of Rho-associated protein kinase (ROCK) including p160Rock (Ki=140nM) and Rock-II. Also acts as a potent inhibitor of agonist-induced Ca2+ sensitization of myosin phosphorylation and smooth muscle contraction. One-hour treatment with 10uM Y-27632 blocks apoptosis of dissociated cultured human embryonic stem cells (hESCs), increases survival and cloning efficiency of hESCs without affecting their pluripotency1. Recently, some reports showed that the application of Y-27632 and Accutase (Cat. No. SCR005), a formulated mixture of digestive enzymes, enhances the post-thaw survival rate of single hESCs using conventional slow freezing and rapid thawing methods
      Product Information
      ApplicationThe ROCK Inhibitor (Y-27632) is available in a 5 mg format & has been optimized & validated for cell culture & Neuroscience applications.
      Key Applications
      • Cell Culture
      • Neuroscience
      Biological Information
      Media FormLiquid
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsBefore Reconstitution: Maintain at -20ºC, protected from light for 2 years. After Reconstitution: 1 year at -20ºC, protected from light
      Packaging Information
      Material Size5 mg
      Transport Information
      Supplemental Information




      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      ROCK Inhibitor (Y-27632) 5 mg2829752
      ROCK Inhibitor (Y-27632) 5 mg3091588
      ROCK Inhibitor (Y-27632) 5 mg2975574
      ROCK Inhibitor (Y-27632) 5 mg2934776
      ROCK Inhibitor (Y-27632) 5 mg - 24275072427507
      ROCK Inhibitor (Y-27632) 5 mg - 20530292053029
      ROCK Inhibitor (Y-27632) 5 mg - 21960692196069
      ROCK Inhibitor (Y-27632) 5 mg - 23257262325726
      ROCK Inhibitor (Y-27632) 5 mg - NG1946963NG1946963
      ROCK Inhibitor (Y-27632) 5 mg - NRG1734711NRG1734711


      Human Stem Cell Systems

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