539624 PKCζ Pseudosubstrate Inhibitor, Myristoylated - Calbiochem

539624
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited AvailabilityLimited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service
      View Pricing & Availability

      Overview

      Replacement Information

      Key Specifications Table

      Empirical Formula
      C₉₀H₁₅₄N₃₀O₁₇

      Pricing & Availability

      Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
      539624-500UG
      Retrieving availability...
      Limited AvailabilityLimited Availability
      Stocked 
      Discontinued
      Limited Quantities Available
      Available
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service
          Contact Customer Service

          Glass bottle 500 μg
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity needs to be mulitiple of
          Upon Order Completion More Information
          You Saved ()
           
          Request Pricing
          Description
          OverviewA cell-permeable, reversible, substrate competitive, myristoylated form of the protein kinase Cζ isozyme pseudosubstrate inhibitory (Cat. No. 539610).
          Catalogue Number539624
          Brand Family Calbiochem®
          SynonymsMyr-SIYRRGARRWRKL-OH, Protein Kinase Cζ Pseudosubstrate Inhibitor, Myristoylated
          References
          ReferencesPowell, D.J., et al. 2003. Mol. Cell Biol. 23, 7794.
          Sajan, M.P., et al. 1999. J. Biol. Chem. 274, 30495.
          Standaert, M.L., et al. 1999. J. Biol. Chem. 274, 14074.
          Laudanna, C., et al. 1998. J. Biol. Chem. 273, 30306.
          Standaert, M.L., et al. 1997. J. Biol. Chem. 272, 30075.
          Product Information
          ATP CompetitiveN
          FormLyophilized
          FormulationSupplied as a trifluoroacetate salt.
          Hill FormulaC₉₀H₁₅₄N₃₀O₁₇
          Chemical formulaC₉₀H₁₅₄N₃₀O₁₇
          Hygroscopic Hygroscopic
          ReversibleY
          Sold on the basis of peptide contentY
          Applications
          Biological Information
          Primary Targetinsulin-stimulated transport in intact adinocytes
          Primary Target IC<sub>50</sub>EC50 = 10-20 µM against insulin-stimulated transport in intact adipocytes
          Purity≥97% by HPLC
          Physicochemical Information
          Cell permeableY
          Peptide ContentY
          Peptide SequenceMyr-Ser-Ile-Tyr-Arg-Arg-Gly-Ala-Arg-Arg-Trp-Arg-Lys-Leu-OH
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          PKCζ Pseudosubstrate Inhibitor, Myristoylated - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          PKCζ Pseudosubstrate Inhibitor, Myristoylated - Calbiochem Certificates of Analysis

          TitleLot Number
          539624

          References

          Reference overview
          Powell, D.J., et al. 2003. Mol. Cell Biol. 23, 7794.
          Sajan, M.P., et al. 1999. J. Biol. Chem. 274, 30495.
          Standaert, M.L., et al. 1999. J. Biol. Chem. 274, 14074.
          Laudanna, C., et al. 1998. J. Biol. Chem. 273, 30306.
          Standaert, M.L., et al. 1997. J. Biol. Chem. 272, 30075.

          Brochure

          Title
          PKC Pathway Poster PDF ( 676 KB )

          Citations

          Title
        • Fishelevich, R., et al. 2006. Journal of Immunology 176, 2590.
        • Mason, J.C., et al. 2004. Journal of Biological Chemistry 279, 41611.
        • Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision11-January-2010 RFH
          SynonymsMyr-SIYRRGARRWRKL-OH, Protein Kinase Cζ Pseudosubstrate Inhibitor, Myristoylated
          DescriptionA cell-permeable, reversible, substrate competitive myristoylated form of protein kinase Cζ pseudo-substrate peptide (Cat. No. 539610) that includes amino acids 113-125 of the pseudosubstrate region. Useful for inhibition studies of PKCζ in intact cells. Reported to inhibit insulin-stimulated glucose transport in intact adipocytes (EC50 = 10-20 µM).
          FormLyophilized
          FormulationSupplied as a trifluoroacetate salt.
          Chemical formulaC₉₀H₁₅₄N₃₀O₁₇
          Peptide SequenceMyr-Ser-Ile-Tyr-Arg-Arg-Gly-Ala-Arg-Arg-Trp-Arg-Lys-Leu-OH
          Purity≥97% by HPLC
          SolubilityH₂O (2 mg/ml)
          Storage -20°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Toxicity Standard Handling
          ReferencesPowell, D.J., et al. 2003. Mol. Cell Biol. 23, 7794.
          Sajan, M.P., et al. 1999. J. Biol. Chem. 274, 30495.
          Standaert, M.L., et al. 1999. J. Biol. Chem. 274, 14074.
          Laudanna, C., et al. 1998. J. Biol. Chem. 273, 30306.
          Standaert, M.L., et al. 1997. J. Biol. Chem. 272, 30075.
          Citation
        • Fishelevich, R., et al. 2006. Journal of Immunology 176, 2590.
        • Mason, J.C., et al. 2004. Journal of Biological Chemistry 279, 41611.