496260 Oncostatin M, Human, Recombinant, E. coli

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: rhOSM

496260
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      Overview

      Replacement Information

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      496260-10UG
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      Limited AvailabilityLimited Availability
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          		 Plastic ampoule 10 μg
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          Description
          OverviewRecombinant, human oncostatin M expressed in E. coli. Pleiotropic cytokine which inhibits growth of A375 melanoma cells and mouse M1 myeloid leukemic cells. Enhances the growth of both endothelial and hematopoietic cells. Has also been reported to have growth stimulatory activities on normal fibroblasts, AIDS-Kaposis sarcoma cells, and a human erythroleukemic cell line, TF-1.
          Catalogue Number496260
          Brand Family Calbiochem®
          SynonymsrhOSM
          References
          ReferencesBoileau, C., et al. 2000. J. Immunol. 164, 5713.
          Miyajima, A., et al. 2000. Cytokine Growth Factor Rev. 11, 177.
          Linsley, P.S., et al. 1990. Mol. Cell. Biol. 10, 1882.
          Kitamura, T., et al. 1989. J. Cell Physiol. 140, 323.
          Product Information
          CAS number106956-32-5
          FormLyophilized
          FormulationLyophilized from sterile-filtered 30% acetonitrile, 0.1% TFA, 50 µg BSA/µg rhOSM.
          Applications
          Biological Information
          Biological activityED₅₀ = 0.15-0.30 ng/ml as measured in a cell proliferation assay using a factor-dependent human erythroleukemic cell line, TF-1
          Purity≥97% by SDS-PAGE
          Physicochemical Information
          ContaminantsEndotoxin: ≤1 EU/µg rhOSM
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage ≤ -70°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 3 months at -70°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          496260

          References

          Reference overview
          Boileau, C., et al. 2000. J. Immunol. 164, 5713.
          Miyajima, A., et al. 2000. Cytokine Growth Factor Rev. 11, 177.
          Linsley, P.S., et al. 1990. Mol. Cell. Biol. 10, 1882.
          Kitamura, T., et al. 1989. J. Cell Physiol. 140, 323.

          Brochure

          Title
          Biologics 32.3 PDF ( 927 KB )
          Growth Factors and Cytokines Technical Bulletin
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision13-August-2008 RFH
          SynonymsrhOSM
          DescriptionRecombinant, human oncostatin M expressed in E. coli. Pleiotropic cytokine which inhibits growth of A375 melanoma cells and mouse M1 myeloid leukemic cells. Has also been reported to have growth stimulatory activities on normal fibroblasts, AIDS-Kaposi's sarcoma cells, and human erythroleukemia cell line, TF-1.
          FormLyophilized
          FormulationLyophilized from sterile-filtered 30% acetonitrile, 0.1% TFA, 50 µg BSA/µg rhOSM.
          CAS number106956-32-5
          Purity≥97% by SDS-PAGE
          ContaminantsEndotoxin: ≤1 EU/µg rhOSM
          Biological activityED₅₀ = 0.15-0.30 ng/ml as measured in a cell proliferation assay using a factor-dependent human erythroleukemic cell line, TF-1
          SolubilityReconstitute to a final concentration of ≥10 µg/ml in sterile PBS containing ≥0.1% BSA or HSA.
          Storage ≤ -70°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 3 months at -70°C.
          Toxicity Standard Handling
          ReferencesBoileau, C., et al. 2000. J. Immunol. 164, 5713.
          Miyajima, A., et al. 2000. Cytokine Growth Factor Rev. 11, 177.
          Linsley, P.S., et al. 1990. Mol. Cell. Biol. 10, 1882.
          Kitamura, T., et al. 1989. J. Cell Physiol. 140, 323.