475820 Mitomycin C, Streptomyces caespitosus, Carrier-Free - CAS 50-07-7 - Calbiochem

475820
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited AvailabilityLimited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service
      View Pricing & Availability
      Click To Print This Page

      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₅H₁₈N₄O₅ 50-07-7

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      475820-10MG
      Retrieving availability...
      Limited AvailabilityLimited Availability
      Stocked 
      Discontinued
      Limited Quantities Available
      Available
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service
          Contact Customer Service

          Glass bottle 10 mg
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity needs to be mulitiple of
          Upon Order Completion More Information
          You Saved ()
           
          Request Pricing
          Description
          OverviewAntibiotic and carcinostatic agent. Inhibits DNA synthesis by cross-linking DNA at guanine and adenine residues; disrupts base pairing. Induces apoptosis in gastric cancer cells. Blocks the cell cycle at the G2 phase. Potency: ≥970 µg/mg.
          Catalogue Number475820
          Brand Family Calbiochem®
          SynonymsMitocin C, MMC
          References
          ReferencesKryt, F.A., et al. 1996. Blood 89, 938.
          Schwartz, G.K., et al. 1995. J. Natl. Cancer Inst. 87, 1394.
          Folnan, R.S., 1993. Oncology 50, 24.
          Tomasz, M., et al. 1987. Science 235, 1204.
          Product Information
          CAS number50-07-7
          FormPurple solid
          Hill FormulaC₁₅H₁₈N₄O₅
          Chemical formulaC₁₅H₁₈N₄O₅
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Biological activityPotency: ≥ 970 μg/mg mitomycin C
          Purity≥95% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSCN0700000
          Safety Information
          R PhraseR: 28

          Very toxic if swallowed.
          S PhraseS: 36/37-45-28

          Wear suitable protective clothing and gloves.
          In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Highly Toxic & Carcinogenic / Teratogenic
          Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          475820

          References

          Reference overview
          Kryt, F.A., et al. 1996. Blood 89, 938.
          Schwartz, G.K., et al. 1995. J. Natl. Cancer Inst. 87, 1394.
          Folnan, R.S., 1993. Oncology 50, 24.
          Tomasz, M., et al. 1987. Science 235, 1204.

          Brochure

          Title
          Antibiotics Profiler
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision30-April-2010 JSW
          SynonymsMitocin C, MMC
          DescriptionAntibiotic and carcinostatic agent. Inhibits DNA synthesis by cross-linking DNA at guanine and adenine residues; disrupts base pairing. Induces apoptosis in gastic cancer cells. Blocks the cell cycle at the G2 phase.
          FormPurple solid
          CAS number50-07-7
          RTECSCN0700000
          Chemical formulaC₁₅H₁₈N₄O₅
          Structure formulaStructure formula
          Purity≥95% by HPLC
          Biological activityPotency: ≥ 970 μg/mg mitomycin C
          SolubilityH₂O (<1 mg/ml) or Methanol (5 mg/ml)
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Highly Toxic & Carcinogenic / Teratogenic
          Merck USA index14, 6215
          ReferencesKryt, F.A., et al. 1996. Blood 89, 938.
          Schwartz, G.K., et al. 1995. J. Natl. Cancer Inst. 87, 1394.
          Folnan, R.S., 1993. Oncology 50, 24.
          Tomasz, M., et al. 1987. Science 235, 1204.