444237 MMP-8 Inhibitor I - CAS 236403-25-1 - Calbiochem

444237
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₇H₁₈N₂O₅S 236403-25-1

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      444237-1MG
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          Plastic ampoule 1 mg
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          Description
          OverviewA potent and cell-permeable inhibitor of MMP-8 (IC50 = 4 nM).
          Catalogue Number444237
          Brand Family Calbiochem®
          Synonyms(3R)-(+)-[2-(4-Methoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3-hydroxamate]
          References
          ReferencesPrager, G.W., et al. 2004. Blood 103, 955.
          Matter, H., et al. 1999. J. Med. Chem. 42, 1908.
          Product Information
          CAS number236403-25-1
          ATP CompetitiveN
          FormWhite solid
          Hill FormulaC₁₇H₁₈N₂O₅S
          Chemical formulaC₁₇H₁₈N₂O₅S
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetMMP-8
          Primary Target IC<sub>50</sub>4 nM
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          444237

          References

          Reference overview
          Prager, G.W., et al. 2004. Blood 103, 955.
          Matter, H., et al. 1999. J. Med. Chem. 42, 1908.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision01-April-2011 RFH
          Synonyms(3R)-(+)-[2-(4-Methoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3-hydroxamate]
          DescriptionA cell-permeable, potent inhibitor of MMP-8 (neutrophil collagenase; IC50 = 4 nM).
          FormWhite solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number236403-25-1
          Chemical formulaC₁₇H₁₈N₂O₅S
          Structure formulaStructure formula
          Purity≥95% by HPLC
          SolubilityDMSO (200 mg/ml)
          Storage -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Toxicity Standard Handling
          ReferencesPrager, G.W., et al. 2004. Blood 103, 955.
          Matter, H., et al. 1999. J. Med. Chem. 42, 1908.