444221 MMP-1/MMP-9 Substrate, Fluorogenic - Calbiochem

444221
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      Overview

      Replacement Information

      Key Specifications Table

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      444221-1MG
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          Plastic ampoule 1 mg
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          Description
          OverviewAn excellent quenched fluorescence substrate for MMP-1 and MMP-9. Both enzymes cleave this substrate between Gly and Cys(Me), liberating a fluorescent cleavage product. Suitable for inhibitor screening and determining Ki values.
          Catalogue Number444221
          Brand Family Calbiochem®
          References
          ReferencesBickett, D.M., et al. 1993. Anal. Biochem. 212, 58.
          Product Information
          ATP CompetitiveN
          FormYellow solid
          Hill FormulaC₄₉H₆₈N₁₄O₁₂S
          Chemical formulaC₄₉H₆₈N₁₄O₁₂S
          ReversibleN
          Applications
          Biological Information
          Primary TargetMMP-1, MMP-9
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableN
          Emission max.
          Excitation max.
          Peptide Sequence{DNP-Pro-Cha-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH₂[Cha = β-cyclohexylalanyl; Abz = 2-aminobenzoyl (anthraniloyl)]
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsUnstable in solution; reconstitute just prior to use.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          444221

          References

          Reference overview
          Bickett, D.M., et al. 1993. Anal. Biochem. 212, 58.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision12-September-2007 JSW
          DescriptionAn excellent quenched fluorescence substrate for MMP-1 and MMP-9 (excitation maximum: 365 nm; emission maximum: 450 nm). Both enzymes cleave this substrate between Gly and Cys(Me), liberating a fluorescent cleavage product. Suitable for inhibitor screening and determining Ki values. Excitation max: ~365 nm; emission max: ~450 nm.
          FormYellow solid
          Intert gas (Yes/No) Packaged under inert gas
          Chemical formulaC₄₉H₆₈N₁₄O₁₂S
          Peptide Sequence{DNP-Pro-Cha-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH₂[Cha = β-cyclohexylalanyl; Abz = 2-aminobenzoyl (anthraniloyl)]
          Purity≥95% by HPLC
          SolubilityH₂O (1 mg/ml)
          Storage -20°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsUnstable in solution; reconstitute just prior to use.
          Toxicity Standard Handling
          ReferencesBickett, D.M., et al. 1993. Anal. Biochem. 212, 58.