MSCRMAG-42K MILLIPLEX MAP Mouse Soluble Cytokine Receptor Magnetic Bead Panel - Immunology Multiplex Assay

MSCRMAG-42K

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Overview

Replacement Information

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Key Specifications Table

Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
sCD30 (sTNFRSF8), sgp130, sIL-1RI (sCD121a), sIL-1RII (sCD121b), sIL-2Rα (sCD25), sIL-4R (sCD124), sIL-6R (sCD126), sRAGE, sTNFRI (sTNFRSF1A), sTNFRII (sTNFRSF1B), sVEGFR1 (sFlt-1), sVEGFR2 (sFlk-1), sVEGFR3 (sFlt-4) M Mplex Luminex xMAP
Description
Catalogue NumberMSCRMAG-42K
Trade Name
  • MILLIPLEX
DescriptionMILLIPLEX MAP Mouse Soluble Cytokine Receptor Magnetic Bead Panel - Immunology Multiplex Assay
OverviewThe MILLIPLEX MAP Mouse Soluble Cytokine Receptor Panel contains 13 metastasis biomarkers that have also been identified in a variety of therapeutic areas. Coupled with the Luminex® xMAP® platform in magnetic bead format, this panel enables researchers to focus on discovery with the advantage of simultaneous quantitative multiplex detection leading to speed and sensitivity.
Background InformationCytokine receptors constitute an integral part of the cytokine biology. Like cytokines, cytokine receptors are involved in normal physiological and pathological processes of almost all disease states. Soluble cytokine receptors naturally arise from genes encoding membrane-bound receptors or are direct derivatives of the receptors themselves. The discovery that soluble cytokine receptors are involved in regulating excessive inflammatory responses and modulating immune events has stimulated significant research interest in their potential role as immunotherapeutic agents. Many of these soluble cytokine receptors have the ability to inhibit the binding and biological activity of their cytokine ligands, making them very specific cytokine antagonists.
References
Product Information
Detection methodLuminex xMAP
ConfigurationDesign your multiplex kit by choosing available analytes within this panel.
Precision, %
  • Intra-assay: < 7
  • Inter-assay: < 12
Panel TypeMAGNETIC Cytokines/Chemokines
Applications
ApplicationSimultaneously analyze multiple cytokine and chemokine biomarkers with Bead-Based Multiplex Assays using the Luminex technology, in mouse serum, plasma and cell culture samples.
Key Applications
  • Multiplexing
Application Notes• An overnight incubation assay is recommended.
• This assay requires 25 μL of 1:5 diluted serum and plasma or tissue/cell culture supernatant
Biological Information
Species Reactivity
  • Mouse
Analytes Available
  • sCD30 (sTNFRSF8)
  • sgp130
  • sIL-1RI (sCD121a)
  • sIL-1RII (sCD121b)
  • sIL-2Rα (sCD25)
  • sIL-4R (sCD124)
  • sIL-6R (sCD126)
  • sRAGE
  • sTNFRI (sTNFRSF1A)
  • sTNFRII (sTNFRSF1B)
  • sVEGFR1 (sFlt-1)
  • sVEGFR2 (sFlk-1)
  • sVEGFR3 (sFlt-4)
Assay PanelEverything you need in a single kit.
Accuracy
  • 89% - 98 %
Physicochemical Information
Sensitivity
  • Refer to kit protocol for sensitivities of individual biomarkers.
Linearity of DilutionContact Technical Service for this information
Standard Curve Range
  • sCD30, sgp130, sIL-6R, sRAGE, sVEGFR1, sVEGFR2, sVEGFR3: 24.4 – 100,000 pg/mL
  • sIL-1RI, sIL-1RII, sIL-2Rα, sIL-4R, sTNFRII: 12.2 – 50,000 pg/mL
  • sTNFRI: 4.9 – 20,000 pg/mL
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Packaging Information
Material Size96-well plate
Transport Information
Supplemental Information
Specifications

Documentation

Protocols

Title
Protocol: Mouse Soluble Cytokine Receptor Magnetic Bead Panel

MILLIPLEX MAP Mouse Soluble Cytokine Receptor Magnetic Bead Panel - Immunology Multiplex Assay SDS

Title

Safety Data Sheet (SDS) 

Brochure

Title
A closer look at immunoassay platforms. Beyond fit for purpse. Bring your biomarkers to life with EMD Millipore Immunoassay Platform Solutions (SigmaMillipore)
Analyte Quarterly Vol 1 2019
Protein Detection Platform and Services Brochure
The Power of Biomarker Analysis

Technical Info

Title
96 well Template 2 Up
96 well Template Single
Quality Control Ranges: Mouse Soluble Cytokine Receptor Magnetic Bead Panel

Data Sheet

Title
Full Service Custom-built Assays

Posters

Title
MILLIPLEX MAP: Exercise, Signaling, and Your Brain (EMD)
MILLIPLEX® MAP Cell Signaling Wall Chart