437650 Lipopolysaccharide, Salmonella typhimurium - Calbiochem

437650
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited AvailabilityLimited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service
      View Pricing & Availability
      Click To Print This Page

      Overview

      Replacement Information

      Key Specifications Table

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      437650-5MG
      Retrieving availability...
      Limited AvailabilityLimited Availability
      Stocked 
      Discontinued
      Limited Quantities Available
      Available
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service
          Contact Customer Service

          Plastic ampoule 5 mg
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity needs to be mulitiple of
          Upon Order Completion More Information
          You Saved ()
           
          Request Pricing
          Description
          OverviewStimulates the activity of inducible nitric oxide synthase. Induces apoptosis in mouse thymus and swine lymphocytes.
          Catalogue Number437650
          Brand Family Calbiochem®
          References
          ReferencesHattori, S., et al. 1995. Biochem. Mol. Biol. Int. 35, 177.
          Mayeux, P.R., et al. 1995. Biochem. Pharmacol. 49, 115.
          Norimatsu, M., et al. 1995. Infect. Immun. 63, 1122.
          Feinstein, D.L., et al. 1993. J. Neurochem. 60, 1945.
          Zhang, Y.H., et al. 1993. Infect. Immun. 61, 5044.
          Product Information
          ATP CompetitiveN
          FormLyophilized
          ReversibleN
          Applications
          Biological Information
          Primary TargetInducible nitric oxide synthase
          Physicochemical Information
          Cell permeableN
          Contaminantsprotein: ≤2%; nucleic acid: ≤2%
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSOJ0895637
          Safety Information
          R PhraseR: 20/21/22

          Harmful by inhalation, in contact with skin and if swallowed.
          S PhraseS: 36

          Wear suitable protective clothing.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Harmful
          Storage +2°C to +8°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Aqueous stock solutions are stable for up to 6 months at 4°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          437650

          References

          Reference overview
          Hattori, S., et al. 1995. Biochem. Mol. Biol. Int. 35, 177.
          Mayeux, P.R., et al. 1995. Biochem. Pharmacol. 49, 115.
          Norimatsu, M., et al. 1995. Infect. Immun. 63, 1122.
          Feinstein, D.L., et al. 1993. J. Neurochem. 60, 1945.
          Zhang, Y.H., et al. 1993. Infect. Immun. 61, 5044.

          Brochure

          Title
          Nitric Oxide and Oxidative Stress Brochure
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision03-June-2013 JSW
          DescriptionEndotoxin lipopolysaccharides initiate a variety of biochemical cell activation pathways (PKC, cAMP-dependent protein kinase, arachidonate metabolism, protein myristoylation, and activation of G-proteins). These unique macromolecules have been extensively studied in order to elucidate and define revelent pathophysiological parameters of endotoxin shock, a profound life-threatening consequence of bacterial sepsis. More recently, these bacterial products have generated intense interest due to their pluripotential immunostimulatory activity, as manifested by the activation of host cells (e.g. B lymphocytes, macrophages) to functional differentiation. Host cells activated by lipopolysaccharides produce a spectrum of hormone-active lymphokines and monokines, including interferons (α, β, and γ), interleukins (IL-1 and IL-6), tumor necrosis factor, platelet activating factor and procoagulant tissue factor. Stimulates the activity of inducible nitric oxide synthase. Induces apoptosis in mouse thymus and swine lymphocytes.
          FormLyophilized
          RTECSOJ0895637
          Contaminantsprotein: ≤2%; nucleic acid: ≤2%
          SolubilityH₂O (5 mg/ml)
          Storage +2°C to +8°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Aqueous stock solutions are stable for up to 6 months at 4°C.
          Toxicity Harmful
          ReferencesHattori, S., et al. 1995. Biochem. Mol. Biol. Int. 35, 177.
          Mayeux, P.R., et al. 1995. Biochem. Pharmacol. 49, 115.
          Norimatsu, M., et al. 1995. Infect. Immun. 63, 1122.
          Feinstein, D.L., et al. 1993. J. Neurochem. 60, 1945.
          Zhang, Y.H., et al. 1993. Infect. Immun. 61, 5044.