434625 Leukotriene B₄ - CAS 71160-24-2 - Calbiochem

434625
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₂₀H₃₂O₄ 71160-24-2

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      434625-50UG
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          Alu drum 50 μg
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          Description
          OverviewPotent proinflammatory agent, primarily because of its actions on polymorphonuclear leukocytes that include chemotaxis, aggregation, degranulation, and stimulation of adherence to vascular endothelium. Stimulates c-fos and c-jun proto-oncogene transcription in human monocytes. Involved in the pathogenesis of postischemic cerebral edema and asthma.
          Catalogue Number434625
          Brand Family Calbiochem®
          SynonymsLTB₄, 5(S),12(R)-Dihydroxy-6-cis-8-trans-10-trans-14-cis-eicosatetraenoic Acid
          References
          ReferencesKendall, A.P., et al. 1995. Anesthesia 50, 590.
          Dokter, W.H., et al. 1994. Leukemia 8, 1181.
          Jedlitschky, G., et al. 1991. J. Biol. Chem. 266, 24763.
          Product Information
          CAS number71160-24-2
          ATP CompetitiveN
          FormClear oil
          FormulationIn Ethanol.
          Hill FormulaC₂₀H₃₂O₄
          Chemical formulaC₂₀H₃₂O₄
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetPolymorphonuclear leukocytes
          Purity>98% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          R PhraseR: 11

          Highly flammable.
          S PhraseS: 16-7

          Keep away from sources of ignition - No Smoking.
          Keep container tightly closed.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Dry Ice Only
          Toxicity Flammable
          Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
          Storage ≤ -70°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          434625

          References

          Reference overview
          Kendall, A.P., et al. 1995. Anesthesia 50, 590.
          Dokter, W.H., et al. 1994. Leukemia 8, 1181.
          Jedlitschky, G., et al. 1991. J. Biol. Chem. 266, 24763.

          Brochure

          Title
          Bioactive Lipids Technical Bulletin
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision14-May-2008 RFH
          SynonymsLTB₄, 5(S),12(R)-Dihydroxy-6-cis-8-trans-10-trans-14-cis-eicosatetraenoic Acid
          DescriptionPotent inflammatory agent, primarily because of its actions on polymorphonuclear leukocytes that include chemotaxis, aggregation, degranulation, and stimulation of adherence to vascular endothelium. Stimulates c-fos and c-jun proto-oncogene transcription in human monocytes. Involved in the pathogenesis of postischemic cerebral edema.
          FormClear oil
          FormulationIn Ethanol.
          CAS number71160-24-2
          Chemical formulaC₂₀H₃₂O₄
          Structure formulaStructure formula
          Purity>98% by HPLC
          SolubilityEthanol
          Storage ≤ -70°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
          Toxicity Flammable
          Merck USA index14, 5455
          ReferencesKendall, A.P., et al. 1995. Anesthesia 50, 590.
          Dokter, W.H., et al. 1994. Leukemia 8, 1181.
          Jedlitschky, G., et al. 1991. J. Biol. Chem. 266, 24763.