420318 Kainic Acid - CAS 487-79-6 - Calbiochem

420318
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₀H₁₅NO₄ 487-79-6

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      420318-10MG
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          Plastic ampoule 10 mg
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          Description
          OverviewAn excitatory amino acid receptor agonist selective for the kainate receptor subtype (Ki = 21 nM for 3H-kainate binding in rat striatum). Also activates AMPA receptors.
          Catalogue Number420318
          Brand Family Calbiochem®
          Synonyms2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic Acid
          References
          ReferencesNiu, L., et al. 1996. Biochemistry 35, 2030.
          Watkins, J.C. and Evans, R.H. 1981. Annu. Rev. Pharmacol. Toxicol. 21, 165.
          Product Information
          CAS number487-79-6
          ATP CompetitiveN
          FormOff-white solid
          Hill FormulaC₁₀H₁₅NO₄
          Chemical formulaC₁₀H₁₅NO₄
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetKainate receptor subtype
          Primary Target K<sub>i</sub>21 nM for 3H-kainate binding in rat striatum
          Purity≥98% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSUX9665250
          Safety Information
          R PhraseR: 20/21/22

          Harmful by inhalation, in contact with skin and if swallowed.
          S PhraseS: 36

          Wear suitable protective clothing.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Harmful
          Storage +2°C to +8°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          420318

          References

          Reference overview
          Niu, L., et al. 1996. Biochemistry 35, 2030.
          Watkins, J.C. and Evans, R.H. 1981. Annu. Rev. Pharmacol. Toxicol. 21, 165.

          Brochure

          Title
          Pathways and Biomarkers of Glutamatergic Synapse Flyer (EMD)
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision13-May-2008 RFH
          Synonyms2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic Acid
          DescriptionAn excitatory amino acid receptor agonist selective for the kainate receptor subtype (Ki = 21 nM for 3H-kainate binding in rat striatum). Also activates AMPA receptors.
          FormOff-white solid
          CAS number487-79-6
          RTECSUX9665250
          Chemical formulaC₁₀H₁₅NO₄
          Structure formulaStructure formula
          Purity≥98% by HPLC
          SolubilityH₂O (10 mg/ml) or dilute base (10 mg/ml)
          Storage +2°C to +8°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
          Toxicity Harmful
          Merck USA index14, 5276
          ReferencesNiu, L., et al. 1996. Biochemistry 35, 2030.
          Watkins, J.C. and Evans, R.H. 1981. Annu. Rev. Pharmacol. Toxicol. 21, 165.