420131 JNK Inhibitor III, Cell-Permeable, Negative Control - Calbiochem

420131
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical Formula
      C₁₉₁H₃₃₆N₇₀O₄₈S

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      420131-1MG
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      Stocked 
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          Plastic ampoule 1 mg
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          Description
          OverviewA cell-permeable 37-mer peptide that contains a scrambled human c-Jun δ domain (amino acids 33-57) sequence linked to that of HIV-TAT protein transduction domain (amino acids 47-57) via a γ-aminobutyric acid (GABA) spacer. Does not disrupt c-Jun/JNK complex formation and thus serves as a negative control for JNK Inhibitor III, Cell-Permeable (Cat. No. 420130).
          Catalogue Number420131
          Brand Family Calbiochem®
          SynonymsHIV-TAT₄₇₋₅₇-gaba-c-JUNδ₃₃₋₅₇, scrambled, Ac-YGRKKRRQRRR-gaba-DSNLIRGVLPTLMPKSLAQNKLKHA-NH₂
          References
          ReferencesHolzberg, D., et al. 2003. J. Biol. Chem. 278, 40213.
          Product Information
          ATP CompetitiveN
          FormLyophilized white solid
          FormulationSupplied as a trifluoroacetate salt.
          Hill FormulaC₁₉₁H₃₃₆N₇₀O₄₈S
          Chemical formulaC₁₉₁H₃₃₆N₇₀O₄₈S
          Hygroscopic Hygroscopic
          ReversibleN
          Applications
          Biological Information
          Primary TargetServes as a negative control for JNK Inhibitor III, Cell-Permeable (Cat. No. 420130).
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableY
          Peptide SequenceAc-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-gaba-Asp-Ser-Asn-Leu-Ile-Arg-Gly-Val-Leu-Pro-Thr-Leu-Met-Pro-Lys-Ser-Leu-Ala-Gln-Asn-Lys-Leu-Lys-His-Ala-NH₂
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          420131

          References

          Reference overview
          Holzberg, D., et al. 2003. J. Biol. Chem. 278, 40213.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision25-July-2008 RFH
          SynonymsHIV-TAT₄₇₋₅₇-gaba-c-JUNδ₃₃₋₅₇, scrambled, Ac-YGRKKRRQRRR-gaba-DSNLIRGVLPTLMPKSLAQNKLKHA-NH₂
          DescriptionA cell-permeable 37 amino acid peptide that contains a scrambled sequence derived from the JNK binding domain (δ) of human c-Jun (amino acids 33-57) fused to the HIV-TAT transduction domain (amino acids 47-57) via a γ-aminobutyric acid (GABA) spacer. Does not disrupt c-Jun/JNK complex formation. Serves as a negative control for JNK Inhibitor III, Cell-Permeable (Cat. No. 420130).
          FormLyophilized white solid
          FormulationSupplied as a trifluoroacetate salt.
          Intert gas (Yes/No) Packaged under inert gas
          Chemical formulaC₁₉₁H₃₃₆N₇₀O₄₈S
          Peptide SequenceAc-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-gaba-Asp-Ser-Asn-Leu-Ile-Arg-Gly-Val-Leu-Pro-Thr-Leu-Met-Pro-Lys-Ser-Leu-Ala-Gln-Asn-Lys-Leu-Lys-His-Ala-NH₂
          Purity≥95% by HPLC
          SolubilityDMSO (1 mg/ml)
          Storage -20°C
          Hygroscopic
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesHolzberg, D., et al. 2003. J. Biol. Chem. 278, 40213.