401474 IKK Inhibitor II, Wedelolactone - CAS 524-12-9 - Calbiochem
IKK Inhibitor II, Wedelolactone, CAS 524-12-9, is a cell-permeable, selective, irreversible inhibitor of IKKα and β kinase activity (IC50 = 10 µM).
More>> IKK Inhibitor II, Wedelolactone, CAS 524-12-9, is a cell-permeable, selective, irreversible inhibitor of IKKα and β kinase activity (IC50 = 10 µM). Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: Wedelolactone, Eclipta alba, 7-Methoxy-5,11,12-trihydroxy-coumestan
Overview
Replacement Information |
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Key Specifications Table
Empirical Formula | CAS # |
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C₁₆H₁₀O₇ | 524-12-9 |
Pricing & Availability
Catalog Number | Availability | Packaging | Qty/Pack | Price | Quantity | |
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401474-1MG |
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Plastic ampoule | 1 mg |
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Product Information | |
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CAS number | 524-12-9 |
ATP Competitive | N |
Form | Yellowish-green, crystalline powder |
Hill Formula | C₁₆H₁₀O₇ |
Chemical formula | C₁₆H₁₀O₇ |
Reversible | N |
Structure formula Image |
Applications | |
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Application | IKK Inhibitor II, Wedelolactone, CAS 524-12-9, is a cell-permeable, selective, irreversible inhibitor of IKKα and β kinase activity (IC50 = 10 µM). |
Biological Information | |
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Primary Target | IKKα and β kinase activity |
Primary Target IC<sub>50</sub> | < 10 µM against IKKα and β kinase activity |
Purity | ≥95% by HPLC |
Physicochemical Information | |
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Cell permeable | Y |
Dimensions |
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Materials Information |
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Toxicological Information |
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Safety Information according to GHS |
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Safety Information |
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Product Usage Statements |
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Packaging Information | |
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Packaged under inert gas | Packaged under inert gas |
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Supplemental Information |
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Specifications |
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Documentation
SDS
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Certificates of Analysis
Title | Lot Number |
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401474 |
References
Reference overview |
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Kobori, M., et al. 2004. Cell Death Differ. 11, 123. Li, C.C., et al. 2003. J. Org. Chem. 68, 8500. Mors, W.B., et al. 1989. Toxicon 27, 1003. Wagner, H., and Fessler, B. 1986. Planta Med. 5, 374. |
Brochure
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Calbiochem Biologics 32.1 |