356780 | Glycyrrhizin, Ammonium Salt - CAS 53956-04-0 - Calbiochem

356780
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₄₂H₆₁O₁₆ • NH₄ 53956-04-0

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      356780-5GM
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          Glass bottle 5 gm
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          Description
          OverviewA triterpenoid saponin isolated from liquorice roots that displays antiviral and anti-tumor activities. Inhibits replication, adsorption, and penetration of severe acute respiratory syndrome-associated coronavirus (SARS-CV), presumably via its ability to upregulate nitric oxide synthase activity. Reported to block the growth of other viruses, including herpes virus, and helps restore liver functions in patients with hepatitis C. It is allso a known 11β-hydroxysteroid dehydrogenase type 2 (11-HSD2) inhibitor.
          Catalogue Number356780
          Brand Family Calbiochem®
          SynonymsGlycyrrhizic Acid, NH₄+
          References
          ReferencesCinatl, J., et al. 2003. Lancet 361, 2045.
          Tanahashi, T., et al. 2002. J. Steroid Biochem. Mol. Biol. 80, 441.
          Kondo, Y., and Takano, F. 1994. Biol. Pharm. Bull. 17, 759.
          Product Information
          CAS number53956-04-0
          FormWhite to off-white solid
          Hill FormulaC₄₂H₆₁O₁₆ • NH₄
          Chemical formulaC₄₂H₆₁O₁₆ • NH₄
          Hygroscopic Hygroscopic
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Purity≥95% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSLZ6500000
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          356780

          References

          Reference overview
          Cinatl, J., et al. 2003. Lancet 361, 2045.
          Tanahashi, T., et al. 2002. J. Steroid Biochem. Mol. Biol. 80, 441.
          Kondo, Y., and Takano, F. 1994. Biol. Pharm. Bull. 17, 759.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision18-January-2017 JSW
          SynonymsGlycyrrhizic Acid, NH₄+
          DescriptionA triterpenoid saponin, isolated from liquorice roots, that exhibits anti-viral and anti-tumor activities. Inhibits replication, adsorption, and penetration of severe acute respiratory syndrome-associated coronavirus (SARS-CV), presumably as a result of its ability to upregulate nitric oxide synthase activity. Also reported to hamper the growth of other viruses, including herpes virus. Shown to restore liver function in patients with hepatitis C virus (HCV). Also shown to inhibit 11β-hydroxysteroid dehydrogenase type 2 (11-HSD2).
          FormWhite to off-white solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number53956-04-0
          RTECSLZ6500000
          Chemical formulaC₄₂H₆₁O₁₆ • NH₄
          Structure formulaStructure formula
          Purity≥95% by HPLC
          SolubilityAqueous NH₄OH (50 mg/ml)
          Storage +2°C to +8°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          Merck USA index14, 4505
          ReferencesCinatl, J., et al. 2003. Lancet 361, 2045.
          Tanahashi, T., et al. 2002. J. Steroid Biochem. Mol. Biol. 80, 441.
          Kondo, Y., and Takano, F. 1994. Biol. Pharm. Bull. 17, 759.