345802 | Gc-Globulin, Mixed Type, Human Plasma

345802
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      Overview

      Replacement Information

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      345802-1MG
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          Plastic ampoule 1 mg
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          Description
          OverviewNative Gc-globulin from human plasma. Single polypeptide chain present in plasma at about 20-55 mg/dl. Functions in binding and transport of vitamin D. May also play an important role in actin homeostasis as it has been shown to bind monomeric actin with high affinity. Binds to cell surface at the DBP binding site in a nonsaturable manner.
          Catalogue Number345802
          Brand Family Calbiochem®
          SynonymsDBP, Vitamin D Binding Protein, Group-specific Component
          References
          ReferencesDi Martino, S.J., and Kew, R.R. 1999. J. Immunol. 163, 2135.
          Lee, W.M., et al. 1987. Hepatology 7, 825.
          Machii, T., et al. 1986. Acta Haematol. 75, 26.
          Product Information
          CAS number68476-36-8
          FormSolid
          FormulationLyophilized from 150 mM NaCl, 20 mM sodium phosphate buffer, pH 7.4.
          Applications
          ApplicationGc-Globulin, Mixed Type, Human Plasma, CAS 68476-36-8, is a single polypeptide chain that transports vitamin D. Binds to cell surface at the DBP binding site in a non-saturable manner.
          Biological Information
          Purity≥95% by SDS-PAGE
          SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 1 year at -70°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          345802

          References

          Reference overview
          Di Martino, S.J., and Kew, R.R. 1999. J. Immunol. 163, 2135.
          Lee, W.M., et al. 1987. Hepatology 7, 825.
          Machii, T., et al. 1986. Acta Haematol. 75, 26.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision30-June-2008 RFH
          SynonymsDBP, Vitamin D Binding Protein, Group-specific Component
          DescriptionNative Gc-globulin from human plasma. A single polypeptide chain present in plasma at a concentration of about 20-55 mg/100 ml. Functions in the binding and transport of vitamin D. May also play an important role in actin homeostasis; binds monomeric actin with high affinity. Binds membranes of both circulating B and T lymphocytes.
          FormSolid
          FormulationLyophilized from 150 mM NaCl, 20 mM sodium phosphate buffer, pH 7.4.
          SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
          CAS number68476-36-8
          Purity≥95% by SDS-PAGE
          Storage -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 1 year at -70°C.
          Toxicity Standard Handling
          ReferencesDi Martino, S.J., and Kew, R.R. 1999. J. Immunol. 163, 2135.
          Lee, W.M., et al. 1987. Hepatology 7, 825.
          Machii, T., et al. 1986. Acta Haematol. 75, 26.