341273 Factor D, Human

341273
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      Overview

      Replacement Information

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      341273-25UG
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      Stocked 
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          Plastic ampoule 25 μg
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          Description
          OverviewNative factor D from human serum. Single-chain glycoprotein composed of 222 amino acids, present in normal human serum at about 1.4 µg/ml. Serine protease that cleaves, and thus activates, Factor B during activation of complement via the alternative pathway. Has recently been shown to be identical to adipsin, a serine protease secreted into the bloodstream by adipocytes.
          Catalogue Number341273
          Brand Family Calbiochem®
          SynonymsC3 Activator Convertase, Adipsin
          References
          ReferencesJing, H., et al. 1999. EMBO J. 18, 804.
          Volankis, J.E., et al. 1985. N. Engl. J. Med. 312, 395.
          Niemann, M.A., et al. 1984. J. Immunol. 132, 809.
          Product Information
          FormLiquid
          FormulationIn PBS, pH 7.2.
          Applications
          Biological Information
          Biological activityIgG, IgA, IgM, Factor H, Factor B, or albumin: ≤trace amounts
          Purity≥90% by SDS-PAGE
          SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Dry Ice Only
          Toxicity Standard Handling
          Storage ≤ -70°C
          Avoid freeze/thaw Avoid freeze/thaw
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          341273

          References

          Reference overview
          Jing, H., et al. 1999. EMBO J. 18, 804.
          Volankis, J.E., et al. 1985. N. Engl. J. Med. 312, 395.
          Niemann, M.A., et al. 1984. J. Immunol. 132, 809.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision24-June-2008 RFH
          SynonymsC3 Activator Convertase, Adipsin
          DescriptionNative factor D from human serum. Single-chain glycoprotein composed of 222 amino acids present in normal human serum at about 1.4 µg/ml. Serine protease that cleaves, and thus activates, Factor B during activation of complement via the alternative pathway. Has recently been shown to be identical to adipsin, a serine protease secreted into the bloodstream by adipocytes.
          FormLiquid
          FormulationIn PBS, pH 7.2.
          SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
          Purity≥90% by SDS-PAGE
          Biological activityIgG, IgA, IgM, Factor H, Factor B, or albumin: ≤trace amounts
          Storage ≤ -70°C
          Avoid freeze/thaw
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
          Toxicity Standard Handling
          ReferencesJing, H., et al. 1999. EMBO J. 18, 804.
          Volankis, J.E., et al. 1985. N. Engl. J. Med. 312, 395.
          Niemann, M.A., et al. 1984. J. Immunol. 132, 809.