324740 | Elastase Substrate V, Fluorogenic - CAS 72252-90-5 - Calbiochem

324740
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      Overview

      Replacement Information

      Key Specifications Table

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      324740-25MG
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          Plastic ampoule 25 mg
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          Description
          OverviewSensitive fluorogenic substrate for the quantitative determination of human leukocyte and porcine pancreatic elastase (Km = 140 µM; kcat/Km = 120,000 M-1 s-1). Not hydrolysed by cathepsin G.
          Catalogue Number324740
          Brand Family Calbiochem®
          SynonymsMeOSuc-AAPV-AMC
          References
          ReferencesBarrett, A.J. 1981. Methods Enzymol. 80, 581.
          Castillo, M.J., et al. 1979. Anal. Biochem. 99, 53.
          Nakajima, K., et al. 1979. J. Biol. Chem. 254, 4027.
          Product Information
          CAS number72252-90-5
          ATP CompetitiveN
          FormWhite to off-white lyophilized solid or powder
          Hill FormulaC₃₁H₄₁N₅O₉
          Chemical formulaC₃₁H₄₁N₅O₉
          ReversibleN
          Applications
          Biological Information
          Primary TargetSensitive fluorogenic substrate for the quantitative determination of human leukocyte and porcine pancreatic elastase
          Primary Target IC<sub>50</sub>Km = 140 µM; kcat/Km = 120,000 M⁻¹ s⁻¹as substrates for human leukocyte and porcine pancreatic elastase
          Purity≥95% by HPLC or TLC
          Physicochemical Information
          Cell permeableN
          Emission max.
          Excitation max.
          Peptide SequenceMeOSuc-Ala-Ala-Pro-Val-AMC
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Protect from Moisture Protect from moisture
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 2 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          324740

          References

          Reference overview
          Barrett, A.J. 1981. Methods Enzymol. 80, 581.
          Castillo, M.J., et al. 1979. Anal. Biochem. 99, 53.
          Nakajima, K., et al. 1979. J. Biol. Chem. 254, 4027.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision09-April-2018 JSW
          SynonymsMeOSuc-AAPV-AMC
          DescriptionSensitive fluorogenic substrate for the quantitative determination of human leukocyte (Km = 140 µM; Kcat/Km = 120,000 s-1 M-1) and porcine pancreatic elastase. Not hydrolyzed by cathepsin G. Excitation max.: ~380 nm; emission max.: ~460 nm.
          FormWhite to off-white lyophilized solid or powder
          CAS number72252-90-5
          Chemical formulaC₃₁H₄₁N₅O₉
          Peptide SequenceMeOSuc-Ala-Ala-Pro-Val-AMC
          Purity≥95% by HPLC or TLC
          SolubilityDMSO (5 mg/ml), DMF (5 mg/ml), or Ethanol (1 mg/ml)
          Storage -20°C
          Protect from moisture
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 2 months at -20°C.
          Toxicity Standard Handling
          ReferencesBarrett, A.J. 1981. Methods Enzymol. 80, 581.
          Castillo, M.J., et al. 1979. Anal. Biochem. 99, 53.
          Nakajima, K., et al. 1979. J. Biol. Chem. 254, 4027.