324696 Elastase Substrate I, Colorimetric - CAS 70967-90-7 - Calbiochem

324696
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      Overview

      Replacement Information

      Key Specifications Table

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      324696-10MG
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          Glass bottle 10 mg
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          Description
          OverviewA specific chromogenic substrate for human neutrophil elastase (Kcat/Km = 120,000 vs. 2700 for pancreatic elastase). Cleavage can be monitored at ~410 nm. Sold on the basis of substrate content.
          Catalogue Number324696
          Brand Family Calbiochem®
          References
          ReferencesBarrett, A.J., et al. 1989. Biochim. J. 260, 259.
          Nakajima, K., et al. 1979. J. Biol. Chem. 254, 4027.
          Product Information
          CAS number70967-90-7
          ATP CompetitiveN
          FormLyophilized
          FormulationLyophilized from a solution containing 90 mg D-mannitol and 10 mg substrate.
          Hill FormulaC₂₇H₃₈N₆O₉
          Chemical formulaC₂₇H₃₈N₆O₉
          ReversibleN
          Applications
          Biological Information
          Primary TargetChromogenic substrate for human neutrophil elastase
          Primary Target IC<sub>50</sub>Kcat/Km = 120,000 vs. 2700 for pancreatic elastase
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableN
          Peptide SequenceMeOSuc-Ala-Ala-Pro-Val-pNA
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Moisture Protect from moisture
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          324696

          References

          Reference overview
          Barrett, A.J., et al. 1989. Biochim. J. 260, 259.
          Nakajima, K., et al. 1979. J. Biol. Chem. 254, 4027.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision12-May-2008 JSW
          DescriptionSpecific chromogenic substrate for human neutrophil elastase (kcat/Km = 120,000 versus pancreatic elastase: kcat/Km = 2,700). Cleavage can be monitored at 410 nm using ε = 8,800.
          FormLyophilized
          FormulationLyophilized from a solution containing 90 mg D-mannitol and 10 mg substrate.
          CAS number70967-90-7
          Chemical formulaC₂₇H₃₈N₆O₉
          Peptide SequenceMeOSuc-Ala-Ala-Pro-Val-pNA
          Purity≥95% by HPLC
          SolubilityH₂O (1 mg/ml)
          Storage -20°C
          Protect from moisture
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesBarrett, A.J., et al. 1989. Biochim. J. 260, 259.
          Nakajima, K., et al. 1979. J. Biol. Chem. 254, 4027.