341006 | EDAC, Hydrochloride

341006
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      Overview

      Replacement Information

      Key Specifications Table

      CAS #Purity
      25952-53-8 ≥98% by Titration

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      341006-25GM
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          Glass bottle 25 gm
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          341006-5GM
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              Plastic ampoule 5 gm
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              Description
              OverviewWater-soluble carbodiimide derivative. Used to modify NMDA receptors. Also useful for conjugating haptens to proteins or polypeptides.
              Molar absorptivity (~212 nm; 50 mM phosphate buffer, pH 8):≥6800 M-1cm-1.
              Catalogue Number341006
              Brand Family Calbiochem®
              SynonymsEDCI, 1-Ethyl-3-(3ʹ-dimethylaminopropyl)carbodiimide, HCl
              References
              ReferencesChazot, P.L., et al. 1993. Biochem. Pharmacol. 45, 605.
              Richardson, A., et al. 1992. Biochem. Pharmacol. 43, 1415.
              Taniuchi, M., et al. 1986. Proc. Natl. Acad. Sci. USA 83, 1950.
              Chase, J.W., et al. 1983. Proc. Natl. Acad. Sci. USA 80, 5480.
              Williams, A., et al. 1981. J. Am. Chem. Soc. 103, 7090.
              Yamada, H., et al. 1981. Biochemistry 20, 4836.
              Thomas, J.O., et al. 1978. J. Mol. Biol. 123, 149.
              Ozawa, H. 1970. Biochemistry 9, 2158.
              Kopple, K.D., et al. 1962. J. Am. Chem. Soc. 84, 4457.
              Product Information
              CAS number25952-53-8
              FormWhite solid
              Hill FormulaC₈H₁₇N₃ · HCl
              Chemical formulaC₈H₁₇N₃ · HCl
              Hygroscopic Hygroscopic
              Structure formula ImageStructure formula Image
              Applications
              Biological Information
              Purity≥98% by Titration
              Physicochemical Information
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              RTECSFF2200000
              Safety Information
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Ambient Temperature Only
              Toxicity Irritant
              Storage -20°C
              Protect from Moisture Protect from moisture
              Hygroscopic Hygroscopic
              Do not freeze Ok to freeze
              Special InstructionsUnstable in solution. Reconstitute just prior to use.
              Packaging Information
              Packaged under inert gas Packaged under inert gas
              Transport Information
              Supplemental Information
              Specifications

              Documentation

              SDS

              Title

              Safety Data Sheet (SDS) 

              Certificates of Analysis

              TitleLot Number
              341006

              References

              Reference overview
              Chazot, P.L., et al. 1993. Biochem. Pharmacol. 45, 605.
              Richardson, A., et al. 1992. Biochem. Pharmacol. 43, 1415.
              Taniuchi, M., et al. 1986. Proc. Natl. Acad. Sci. USA 83, 1950.
              Chase, J.W., et al. 1983. Proc. Natl. Acad. Sci. USA 80, 5480.
              Williams, A., et al. 1981. J. Am. Chem. Soc. 103, 7090.
              Yamada, H., et al. 1981. Biochemistry 20, 4836.
              Thomas, J.O., et al. 1978. J. Mol. Biol. 123, 149.
              Ozawa, H. 1970. Biochemistry 9, 2158.
              Kopple, K.D., et al. 1962. J. Am. Chem. Soc. 84, 4457.

              Brochure

              Title
              Excitotoxic Glutamate Analogs Technical Bulletin
              Data Sheet

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision17-October-2017 JSW
              SynonymsEDCI, 1-Ethyl-3-(3ʹ-dimethylaminopropyl)carbodiimide, HCl
              DescriptionWater-soluble derivative of carbodiimide useful for conjugating haptens to proteins and polypeptides. Used to modify NMDA receptors and as a condensing agent in peptide synthesis. The major advantage of EDAC coupling is the easy removal of excess reagent and the corresponding urea by washing with dilute acid or water. Carbodiimides catalyze the formation of amide bonds, carboxylic acids, and amines by activating the carboxylate to form an O-acylurea. This intermediate can be attacked by an amine directly to form an amide. EDAC is released as a soluble urea derivative.
              FormWhite solid
              Intert gas (Yes/No) Packaged under inert gas
              CAS number25952-53-8
              RTECSFF2200000
              Chemical formulaC₈H₁₇N₃ · HCl
              Structure formulaStructure formula
              Purity≥98% by Titration
              SolubilityH₂O (2-5 mg/ml) or Aqueous buffers (2-5 mg/ml). Avoid amine containing buffers.
              Storage -20°C
              Hygroscopic
              Protect from moisture
              Do Not Freeze Ok to freeze
              Special InstructionsUnstable in solution. Reconstitute just prior to use.
              Toxicity Irritant
              ReferencesChazot, P.L., et al. 1993. Biochem. Pharmacol. 45, 605.
              Richardson, A., et al. 1992. Biochem. Pharmacol. 43, 1415.
              Taniuchi, M., et al. 1986. Proc. Natl. Acad. Sci. USA 83, 1950.
              Chase, J.W., et al. 1983. Proc. Natl. Acad. Sci. USA 80, 5480.
              Williams, A., et al. 1981. J. Am. Chem. Soc. 103, 7090.
              Yamada, H., et al. 1981. Biochemistry 20, 4836.
              Thomas, J.O., et al. 1978. J. Mol. Biol. 123, 149.
              Ozawa, H. 1970. Biochemistry 9, 2158.
              Kopple, K.D., et al. 1962. J. Am. Chem. Soc. 84, 4457.