407129 D-myo-Inositol 1,4,5-Trisphosphate, 3-Deoxy-3-fluoro-, Hexasodium Salt - CAS 129365-68-0 - Calbiochem

407129
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₆H₈FO₁₄P₃ · 6Na 129365-68-0

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      407129-100UG
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          Plastic ampoule 100 μg
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          Description
          OverviewEquipotent to Ins(1,4,5)P3 in releasing intracellular calcium. The 3-position is blocked by fluorine, hence it cannot be converted to Ins(1,3,4,5)P4 by the action of 3-kinases. May be a useful tool for studying the complex biochemical pathways in which InsP3 and InsP4 are closely interactive.
          Catalogue Number407129
          Brand Family Calbiochem®
          Synonyms3-F-Ins(1,4,5)P₃, 6Na
          References
          ReferencesRubinstein, E., et al. 1992. Blood 79, 2901.
          Kozikowski, A.P., et al. 1990. J. Am. Chem. Soc. 112, 7403.
          Bartha, K., et al. 1989. Biochem. J. 263, 149.
          Product Information
          CAS number129365-68-0
          ATP CompetitiveN
          FormWhite crystalline solid
          Hill FormulaC₆H₈FO₁₄P₃ · 6Na
          Chemical formulaC₆H₈FO₁₄P₃ · 6Na
          Hygroscopic Hygroscopic
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetReleasing intracellular calcium
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          407129

          References

          Reference overview
          Rubinstein, E., et al. 1992. Blood 79, 2901.
          Kozikowski, A.P., et al. 1990. J. Am. Chem. Soc. 112, 7403.
          Bartha, K., et al. 1989. Biochem. J. 263, 149.

          Brochure

          Title
          Calcium Metabolism and Related Products Brochure
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision14-July-2008 RFH
          Synonyms3-F-Ins(1,4,5)P₃, 6Na
          DescriptionEquipotent to Ins(1,4,5)P3 in releasing intracellular calcium. The 3-position is blocked by fluorine so it cannot be converted to Ins(1,3,4,5)P4 by the action of 3-kinases. May be a useful tool for studying the complex biochemical pathways in which InsP3 and InsP4 are closely interactive.
          FormWhite crystalline solid
          CAS number129365-68-0
          Chemical formulaC₆H₈FO₁₄P₃ · 6Na
          Structure formulaStructure formula
          SolubilityH₂O (1 mg/ml)
          Storage -20°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesRubinstein, E., et al. 1992. Blood 79, 2901.
          Kozikowski, A.P., et al. 1990. J. Am. Chem. Soc. 112, 7403.
          Bartha, K., et al. 1989. Biochem. J. 263, 149.

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          Categories

          Life Science Research > Inhibitors and Biochemicals > Biochemicals > Lipids > Phosphoinositides, Phospholipids and Related Products