239900 Cypermethrin - CAS 52315-07-8 - Calbiochem

239900
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₂₂H₁₉Cl₂NO₃ 52315-07-8

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      239900-10MG
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          Alu drum 10 mg
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          Description
          OverviewSynthetic type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B; IC50 = 40 pM). May also have varied effects on ion channels.
          Catalogue Number239900
          Brand Family Calbiochem®
          Synonyms(R,S)-α-Cyano-3-phenoxybenzyl-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
          References
          ReferencesRichter, A., et al. 1995. Biochem. Pharmacol. 49, 367.
          Wang, J.H., and Stelzer, A. 1994. NeuroReport 5, 2377.
          Enan, E., and Matsumura, F. 1992. Biochem. Pharmacol. 43, 1777.
          Narahasi, T. 1992. Trends Pharmacol. Sci. 13, 236.
          Product Information
          CAS number52315-07-8
          ATP CompetitiveN
          FormOil
          Hill FormulaC₂₂H₁₉Cl₂NO₃
          Chemical formulaC₂₂H₁₉Cl₂NO₃
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary Targetcalcineurin
          Primary Target IC<sub>50</sub>40 pM against calcineurin (protein phosphatase 2B
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSGZ1250000
          Safety Information
          R PhraseR: 25-36/38

          Toxic if swallowed.
          Irritating to eyes and skin.
          S PhraseS: 26-36/37/39-45

          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Wear suitable protective clothing, gloves and eye/face protection.
          In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Toxic
          Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
          Storage +2°C to +8°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          239900

          References

          Reference overview
          Richter, A., et al. 1995. Biochem. Pharmacol. 49, 367.
          Wang, J.H., and Stelzer, A. 1994. NeuroReport 5, 2377.
          Enan, E., and Matsumura, F. 1992. Biochem. Pharmacol. 43, 1777.
          Narahasi, T. 1992. Trends Pharmacol. Sci. 13, 236.

          Brochure

          Title
          Protease and Phosphatase Inhibitor Cocktails Brochure
          Protein Phosphatases Technical Bulletin

          Citations

          Title
        • Mike T. Lin, et al. (2005) Ca2+-activated K+ channel-associated phosphatase and kinase activities during development. American Journal of Physiology Heart and Circulatory Physiology 289, H414-H425.
        • Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision29-February-2008 JSW
          Synonyms(R,S)-α-Cyano-3-phenoxybenzyl-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
          DescriptionType II pyrethroid insecticide. Potent inhibitor of calcineurin (protein phosphatase 2B, IC50 = 40 pM). May also have varied effects on ion channels.
          FormOil
          CAS number52315-07-8
          RTECSGZ1250000
          Chemical formulaC₂₂H₁₉Cl₂NO₃
          Structure formulaStructure formula
          Purity≥95% by HPLC
          SolubilityDMSO (15 mg/ml) or Ethanol (5 mg/ml)
          Storage +2°C to +8°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Toxic
          Merck USA index14, 2767
          ReferencesRichter, A., et al. 1995. Biochem. Pharmacol. 49, 367.
          Wang, J.H., and Stelzer, A. 1994. NeuroReport 5, 2377.
          Enan, E., and Matsumura, F. 1992. Biochem. Pharmacol. 43, 1777.
          Narahasi, T. 1992. Trends Pharmacol. Sci. 13, 236.
          Citation
        • Mike T. Lin, et al. (2005) Ca2+-activated K+ channel-associated phosphatase and kinase activities during development. American Journal of Physiology Heart and Circulatory Physiology 289, H414-H425.