234505 Compound 56 - CAS 171745-13-4 - Calbiochem

234505
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited AvailabilityLimited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service
      View Pricing & Availability
      Click To Print This Page

      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₈H₁₈BrN₃O₂ 171745-13-4

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      234505-500UG
      Retrieving availability...
      Limited AvailabilityLimited Availability
      Stocked 
      Discontinued
      Limited Quantities Available
      Available
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service
          Contact Customer Service

          Plastic ampoule 500 μg
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity needs to be mulitiple of
          Upon Order Completion More Information
          You Saved ()
           
          Request Pricing
          Description
          OverviewA cell-permeable, reversible, ATP-competitive, highly potent and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (IC50 = 6 pM).
          Catalogue Number234505
          Brand Family Calbiochem®
          Synonyms4-[(3-Bromophenyl)amino]-6,7-diethoxyquinazoline
          References
          ReferencesBridges, A.J., et al. 1996. J. Med. Chem. 39, 267.
          Product Information
          CAS number171745-13-4
          ATP CompetitiveY
          DeclarationSold under license of U.S. Patent 5,457,105 and European Patent 0,566,266.
          FormWhite solid
          Hill FormulaC₁₈H₁₈BrN₃O₂
          Chemical formulaC₁₈H₁₈BrN₃O₂
          ReversibleY
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetEGFR
          Primary Target IC<sub>50</sub>6 pM against EGFR
          Purity≥97% by HPLC
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          R PhraseR: 40

          Limited evidence of a carcinogenic effect.
          S PhraseS: 36

          Wear suitable protective clothing.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Carcinogenic / Teratogenic
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          234505

          References

          Reference overview
          Bridges, A.J., et al. 1996. J. Med. Chem. 39, 267.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision12-January-2010 RFH
          Synonyms4-[(3-Bromophenyl)amino]-6,7-diethoxyquinazoline
          DescriptionA cell-permeable, reversible, ATP-competitive, highly potent and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC50 = 6 pM).
          FormWhite solid
          CAS number171745-13-4
          Chemical formulaC₁₈H₁₈BrN₃O₂
          Structure formulaStructure formula
          Purity≥97% by HPLC
          SolubilityDMSO (200 mg/ml)
          Storage -20°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Carcinogenic / Teratogenic
          ReferencesBridges, A.J., et al. 1996. J. Med. Chem. 39, 267.