218776 Caspase-9 Inhibitor II, Cell-Permeable - Calbiochem

218776
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical Formula
      C₉₇H₁₆₂N₂₂O₂₅

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      218776-1MG
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          Glass bottle 1 mg
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          Description
          OverviewA potent, cell-permeable, and reversible inhibitor of caspase-9. May also inhibit caspase-4 and caspase-5. The N-terminal sequence (amino acids 1-16) corresponds to the hydrophobic region of the signal peptide of Kaposi fibroblast growth factor and confers cell permeability to the peptide.
          Catalogue Number218776
          Brand Family Calbiochem®
          SynonymsLEHD-CHO, Cell-permeable
          References
          ReferencesThornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
          Product Information
          ATP CompetitiveN
          FormWhite lyophilized solid
          FormulationSupplied as a trifluoroacetate salt.
          Hill FormulaC₉₇H₁₆₂N₂₂O₂₅
          Chemical formulaC₉₇H₁₆₂N₂₂O₂₅
          Hygroscopic Hygroscopic
          ReversibleY
          Applications
          Biological Information
          Primary Targetcaspase-4, caspase-5, caspase-9
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableY
          Peptide SequenceAc-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Leu-Glu-His-Asp-CHO
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          218776

          References

          Reference overview
          Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision04-June-2008 RFH
          SynonymsLEHD-CHO, Cell-permeable
          DescriptionA potent, cell-permeable and reversible inhibitor or caspase-9.
          FormWhite lyophilized solid
          FormulationSupplied as a trifluoroacetate salt.
          Chemical formulaC₉₇H₁₆₂N₂₂O₂₅
          Peptide SequenceAc-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Leu-Glu-His-Asp-CHO
          Purity≥95% by HPLC
          SolubilityDMSO (5 mg/ml)
          Storage -20°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesThornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.