217503 Cardiotoxin, Naja pallida

217503
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      Overview

      Replacement Information

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      217503-1MG
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          Glass bottle 1 mg
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          Description
          OverviewA cytolytic toxin that causes depolarization of skeletal muscle fibers in vitro. Stimulates Ca2+ transport and ATP hydrolysis by the sarcolemmal Ca2+/Mg2+-ATPase. Its action is strongly potentiated by phospholipase A2. Inhibits protein kinase C (IC50 = 1.8 µM).
          Catalogue Number217503
          Brand Family Calbiochem®
          References
          ReferencesJang, J.Y., et al. 1997. Biochemistry 36, 4635.
          Huang, J.L., and Trumble, W.R. 1991. Toxicon 29, 31.
          Raynor, R.L., et al. 1991. J. Biol. Chem. 266, 2753.
          Grognet, J.M., et al. 1986. Mol. Immunol. 23, 132.
          Product Information
          CAS number11061-96-4
          DeclarationNot available for sale outside of the United States.
          FormLyophilized solid
          Applications
          Biological Information
          Purity≥95% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSFH7482450
          Safety Information
          R PhraseR: 20/21/22

          Harmful by inhalation, in contact with skin and if swallowed.
          S PhraseS: 36

          Wear suitable protective clothing.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Harmful
          Storage +2°C to +8°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          217503

          References

          Reference overview
          Jang, J.Y., et al. 1997. Biochemistry 36, 4635.
          Huang, J.L., and Trumble, W.R. 1991. Toxicon 29, 31.
          Raynor, R.L., et al. 1991. J. Biol. Chem. 266, 2753.
          Grognet, J.M., et al. 1986. Mol. Immunol. 23, 132.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision13-June-2016 JSW
          DescriptionA cytolytic toxin that causes depolarization of skeletal muscle fibers in vitro. Stimulates Ca2+ transport and ATP hydrolysis by sarcolemmal Ca2+/Mg2+-ATPase. Its action is strongly potentiated by phospholipase A2. Inhibits protein kinase C (IC50 = 1.8 µM).
          FormLyophilized solid
          CAS number11061-96-4
          RTECSFH7482450
          Purity≥95% by HPLC
          SolubilityH₂O (1 mg/ml)
          Storage +2°C to +8°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Harmful
          Merck USA index14, 1835
          ReferencesJang, J.Y., et al. 1997. Biochemistry 36, 4635.
          Huang, J.L., and Trumble, W.R. 1991. Toxicon 29, 31.
          Raynor, R.L., et al. 1991. J. Biol. Chem. 266, 2753.
          Grognet, J.M., et al. 1986. Mol. Immunol. 23, 132.