208731 | Calpain Substrate II, Fluorogenic - CAS 94367-20-1 - Calbiochem

208731
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      Overview

      Replacement Information

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      208731-25MG
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          Plastic ampoule 25 mg
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          Description
          OverviewCyclic fluorogenic substrate for the quantitative determination of calpain -1 and -2. Also suitable for measuring the peptidase activity of the 20S proteasome. Typical concentrations range from 10 - 100 µM, depending on assay conditions.
          Catalogue Number208731
          Brand Family Calbiochem®
          SynonymsSuc-LY-AMC
          References
          ReferencesSeol, J.H., et al. 1989. FEBS Lett. 247, 197.
          Woo, K.M., et al. 1989. J. Biol. Chem. 264, 2088.
          Sasaki, T., et al. 1984. J. Biol. Chem. 259, 12489.
          Product Information
          CAS number94367-20-1
          ATP CompetitiveN
          FormOff-white solid
          Hill FormulaC₂₉H₃₁N₃O₇
          Chemical formulaC₂₉H₃₁N₃O₇
          ReversibleN
          Applications
          Biological Information
          Primary TargetCalpain -1 and -2
          Purity≥95% by TLC
          Physicochemical Information
          Cell permeableN
          Emission max.
          Excitation max.
          Peptide SequenceSuc-Leu-Tyr-AMC
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Protect from Moisture Protect from moisture
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          208731

          References

          Reference overview
          Seol, J.H., et al. 1989. FEBS Lett. 247, 197.
          Woo, K.M., et al. 1989. J. Biol. Chem. 264, 2088.
          Sasaki, T., et al. 1984. J. Biol. Chem. 259, 12489.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision28-May-2008 RFH
          SynonymsSuc-LY-AMC
          DescriptionFluorogenic substrate for the quantitative determination of porcine calpain I and II activity. Also serves as a substrate for other proteases including proteasome. (excitation wavelength: 380 nm; emission wavelength: 460 nm)
          FormOff-white solid
          CAS number94367-20-1
          Chemical formulaC₂₉H₃₁N₃O₇
          Peptide SequenceSuc-Leu-Tyr-AMC
          Purity≥95% by TLC
          SolubilityDMSO
          Storage -20°C
          Protect from moisture
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Toxicity Standard Handling
          ReferencesSeol, J.H., et al. 1989. FEBS Lett. 247, 197.
          Woo, K.M., et al. 1989. J. Biol. Chem. 264, 2088.
          Sasaki, T., et al. 1984. J. Biol. Chem. 259, 12489.