208775 CaMKP Inhibitor - CAS 52789-62-5 - Calbiochem

208775
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₀H₈NNaO₇S₂ • 2H₂O 52789-62-5

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      208775-100MG
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          Glass bottle 100 mg
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          Description
          OverviewAn amino-naphthol sulfonic acid that acts as a substrate-competitive inhibitor of Ca2+/calmodulin-dependent protein kinase phosphatase (CaMKP) and its nuclear isoform CaMKP-N (IC50 = 6.4 and 6.6 µM, respectively), while exhibiting little activity against PP2B/CaN and PP2C (<10% inhibition at 10 µM).
          Catalogue Number208775
          Brand Family Calbiochem®
          Synonyms1-Amino-8-naphthol-2,4-disulfonic acid, Na salt, dihydrate, Ca2+/Calmodulin-dependent Protein Kinase Phosphatase Inhibitor
          References
          ReferencesSueyoshi, N., et al. 2007. Biochem. Biophys. Res. Commun. 363, 715.
          Product Information
          CAS number52789-62-5
          FormYellow solid
          Hill FormulaC₁₀H₈NNaO₇S₂ • 2H₂O
          Chemical formulaC₁₀H₈NNaO₇S₂ • 2H₂O
          Hygroscopic Hygroscopic
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Purity≥85% by Titration
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          S PhraseS: 22-24/25

          Do not breathe dust.
          Avoid contact with skin and eyes.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          208775

          References

          Reference overview
          Sueyoshi, N., et al. 2007. Biochem. Biophys. Res. Commun. 363, 715.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision07-October-2008 RFH
          Synonyms1-Amino-8-naphthol-2,4-disulfonic acid, Na salt, dihydrate, Ca2+/Calmodulin-dependent Protein Kinase Phosphatase Inhibitor
          DescriptionAn amino-naphthol sulfonic acid that acts as a substrate-competitive inhibitor of Ca2+/calmodulin-dependent protein kinase phosphatase (CaMKP) and its nuclear isoform CaMKP-N (IC50 = 6.4 and 6.6 µM, respectively), while exhibiting little activity against PP2B/CaN and PP2C (<10% inhibition at 10 µM).
          FormYellow solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number52789-62-5
          Chemical formulaC₁₀H₈NNaO₇S₂ • 2H₂O
          Structure formulaStructure formula
          Purity≥85% by Titration
          SolubilityH₂O (1 mg/ml)
          Storage +2°C to +8°C
          Hygroscopic
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Toxicity Standard Handling
          ReferencesSueyoshi, N., et al. 2007. Biochem. Biophys. Res. Commun. 363, 715.