286888 BHQ - CAS 88-58-4 - Calbiochem

286888
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₄H₂₂O₂ 88-58-4

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      286888-100MG
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          Plastic ampoule 100 mg
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          Description
          OverviewMobilizes Ca2+ specifically from Ins(1,4,5)P3-sensitive Ca2+ stores by inhibiting microsomal and sarcoplasmic reticulum Ca2+-ATPase activity. Does not affect mitochondrial Ca2+ fluxes or plasma membrane Ca2+/Mg2+ ATPase activity. Inhibits prostaglandin E2 and prostacyclin formation in osteoblast-like cell lines.
          Catalogue Number286888
          Brand Family Calbiochem®
          Synonyms2,5-Di-(t-butyl)-1,4-hydroquinone, t-BuBHQ
          References
          ReferencesSalvador, J.M., and Mata, A.M. 1998. Arch. Biochem. Biophys. 351, 272.
          Leis, H.J., et al. 1996. Br. J. Pharmacol. 117, 540.
          Khan, Y.M., et al. 1995. Biochemistry 34, 14385.
          Hassessian, H., et al. 1994. Br. J. Pharmacol. 112, 1118.
          Khodorova, A.B., and Astashkin, E.I. 1994. FEBS Lett. 353, 167.
          Schilling, W.P., et al. 1992. Biochem. J. 284, 521.
          Wictome, M., et al. 1992. FEBS Lett. 304, 109.
          Mason, M.J., et al. 1991. J. Biol. Chem. 266, 20856.
          Kass, G.N., et al. 1989. J. Biol. Chem. 264, 15192.
          Product Information
          CAS number88-58-4
          ATP CompetitiveN
          FormWhite solid
          Hill FormulaC₁₄H₂₂O₂
          Chemical formulaC₁₄H₂₂O₂
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary Targetmicosomal and sarcoplasmic reticulation Ca2+ ATPase activity
          Purity≥99% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSMX5160000
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +15°C to +30°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          286888

          References

          Reference overview
          Salvador, J.M., and Mata, A.M. 1998. Arch. Biochem. Biophys. 351, 272.
          Leis, H.J., et al. 1996. Br. J. Pharmacol. 117, 540.
          Khan, Y.M., et al. 1995. Biochemistry 34, 14385.
          Hassessian, H., et al. 1994. Br. J. Pharmacol. 112, 1118.
          Khodorova, A.B., and Astashkin, E.I. 1994. FEBS Lett. 353, 167.
          Schilling, W.P., et al. 1992. Biochem. J. 284, 521.
          Wictome, M., et al. 1992. FEBS Lett. 304, 109.
          Mason, M.J., et al. 1991. J. Biol. Chem. 266, 20856.
          Kass, G.N., et al. 1989. J. Biol. Chem. 264, 15192.

          Brochure

          Title
          Calcium Metabolism and Related Products Brochure
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision17-June-2008 RFH
          Synonyms2,5-Di-(t-butyl)-1,4-hydroquinone, t-BuBHQ
          DescriptionMobilizes Ca2+ specifically from the Ins(1,4,5)P3-sensitive Ca2+ stores by inhibiting microsomal and sarcoplasmic reticulum Ca2+-ATPase activity. Does not affect mitochondrial Ca2+ fluxes or plasma membrane Ca2+/Mg2+ ATPase activity. Useful for the study of endomembrane Ca2+ stores and plasma membrane Ca2+ permeability pathways.
          FormWhite solid
          CAS number88-58-4
          RTECSMX5160000
          Chemical formulaC₁₄H₂₂O₂
          Structure formulaStructure formula
          Purity≥99% by HPLC
          SolubilityEthanol (25 mg/ml), Methanol, or DMSO (1 mM)
          Storage +15°C to +30°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesSalvador, J.M., and Mata, A.M. 1998. Arch. Biochem. Biophys. 351, 272.
          Leis, H.J., et al. 1996. Br. J. Pharmacol. 117, 540.
          Khan, Y.M., et al. 1995. Biochemistry 34, 14385.
          Hassessian, H., et al. 1994. Br. J. Pharmacol. 112, 1118.
          Khodorova, A.B., and Astashkin, E.I. 1994. FEBS Lett. 353, 167.
          Schilling, W.P., et al. 1992. Biochem. J. 284, 521.
          Wictome, M., et al. 1992. FEBS Lett. 304, 109.
          Mason, M.J., et al. 1991. J. Biol. Chem. 266, 20856.
          Kass, G.N., et al. 1989. J. Biol. Chem. 264, 15192.