ST1033 Anti-Shc Rabbit pAb

ST1033
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityHostAntibody Type
      H, M, R Rb Polyclonal Antibody

      Pricing & Availability

      Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
      ST1033-50UG
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          Plastic ampoule 50 μg
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          Description
          OverviewRecognizes the ~46, ~55, and ~66 kDa isoforms of Shc in EGF-treated A431 cells.
          Catalogue NumberST1033
          Brand Family Calbiochem®
          References
          ReferencesHumtsoe, J.O., et al. 2003. EMBO J. 22, 1539.
          Wary, K.K, et al. 1988. Cell 94, 625
          Product Information
          FormLiquid
          Positive controlA431 cells stimulated with EGF
          PreservativeNone
          Applications
          Key Applications Immunoprecipitation
          Enzyme-Linked Immunosorbent Assay
          Immunocytochemistry
          Immunohistochemistry
          Application NotesELISA (1:1000-1:100,000)
          Immunofluorescence (20-50 µg/ml, indirect)
          Immunohistochemistry (20-50 µg/ml)
          Immunoprecipitation (1-4 µg/mg protein)
          Application CommentsAntibody should be titrated for optimal results in individual systems.
          Biological Information
          Immunogena recombinant protein consisting of the Sh2 domain of human Shc, fused to GST
          ImmunogenHuman
          HostRabbit
          IsotypeIgG
          Species Reactivity
          • Human
          • Mouse
          • Rat
          Antibody TypePolyclonal Antibody
          Concentration Label Please refer to vial label for lot-specific concentration
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Blue Ice Only
          Toxicity Standard Handling
          Storage -20°C
          Avoid freeze/thaw Avoid freeze/thaw
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Anti-Shc Rabbit pAb SDS

          Title

          Safety Data Sheet (SDS) 

          Anti-Shc Rabbit pAb Certificates of Analysis

          TitleLot Number
          ST1033

          References

          Reference overview
          Humtsoe, J.O., et al. 2003. EMBO J. 22, 1539.
          Wary, K.K, et al. 1988. Cell 94, 625
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision16-September-2010 RFH
          ApplicationELISA (1:1000-1:100,000)
          Immunofluorescence (20-50 µg/ml, indirect)
          Immunohistochemistry (20-50 µg/ml)
          Immunoprecipitation (1-4 µg/mg protein)
          DescriptionImmunoaffinity purified rabbit polyclonal antibody. Recognizes the ~46, ~55, and ~66 kDa isoforms of Shc.
          BackgroundShc is an SH2-PTB domain adaptor protein that links various tyrosine kinases to Ras by recruiting the Grb2/SOS complex to the plasma membrane. Note that the ~66 kDa isoform is not typically expressed in hematapoetic cells.
          HostRabbit
          Immunogen speciesHuman
          Immunogena recombinant protein consisting of the Sh2 domain of human Shc, fused to GST
          IsotypeIgG
          Specieshuman, mouse, rat
          Positive controlA431 cells stimulated with EGF
          FormLiquid
          Concentration Label Please refer to vial label for lot-specific concentration
          PreservativeNone
          CommentsAntibody should be titrated for optimal results in individual systems.
          Storage -20°C
          Avoid freeze/thaw
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Toxicity Standard Handling
          ReferencesHumtsoe, J.O., et al. 2003. EMBO J. 22, 1539.
          Wary, K.K, et al. 1988. Cell 94, 625