438190 Anti-LRP, Heavy Chain Mouse mAb (8G1)

438190
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityHostAntibody Type
      H M Monoclonal Antibody

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      438190-100UG
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      Stocked 
      Discontinued
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      Available
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          Will advise
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          Contact Customer Service

          Glass bottle 100 μg
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          Description
          OverviewRecognizes the ~515 kDa LRP heavy chain protein.
          Catalogue Number438190
          Brand Family Calbiochem®
          SynonymsAnti-Low Density Lipoprotein Receptor-Related Protein
          References
          ReferencesMikhailenko, I., et al. 2001. J. Biol. Chem. 276, 39484.
          Rebeck, W.G., et al. 2001. Mol. Brain Res. 87, 238.
          Strickland, D.K., et al. 1990. J. Biol. Chem. 265, 17401.
          Product Information
          FormLiquid
          FormulationIn 100 mM NaCl, 50 mM phosphate buffer, pH 7.4.
          PreservativeNone
          Applications
          Key Applications Immunoprecipitation
          Neutralization Studies
          Paraffin Sections
          Enzyme-Linked Immunosorbent Assay
          Flow Cytometry
          Immunoblotting (Western Blotting)
          Application NotesELISA (see comments)
          Flow Cytometry (see comments)
          Immunoblotting (1-5 µg/ml)
          Immunoprecipitation (see comments)
          Paraffin Sections (1-10 µg/ml)
          Neutralization Studies (see comments)
          Application CommentsRecognizes the low density heavy chain (~515 kDa) by immunoblotting under non-reducing conditions. This antibody has also been reported to work for immunoprecipitation, flow cytometry, and ELISA. Variables associated with assay conditions will dictate the proper working dilution.
          Biological Information
          Immunogennative LRP from human placenta
          ImmunogenHuman
          Clone8G1
          HostMouse
          IsotypeIgG₁
          Species Reactivity
          • Human
          Antibody TypeMonoclonal Antibody
          Concentration Label Please refer to vial label for lot-specific concentration
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Dry Ice Only
          Toxicity Standard Handling
          Storage -20°C
          Avoid freeze/thaw Avoid freeze/thaw
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          438190

          References

          Reference overview
          Mikhailenko, I., et al. 2001. J. Biol. Chem. 276, 39484.
          Rebeck, W.G., et al. 2001. Mol. Brain Res. 87, 238.
          Strickland, D.K., et al. 1990. J. Biol. Chem. 265, 17401.

          Brochure

          Title
          Antibody Sourcebook!" Second Edition
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision07-August-2007 RFH
          SynonymsAnti-Low Density Lipoprotein Receptor-Related Protein
          ApplicationELISA (see comments)
          Flow Cytometry (see comments)
          Immunoblotting (1-5 µg/ml)
          Immunoprecipitation (see comments)
          Paraffin Sections (1-10 µg/ml)
          Neutralization Studies (see comments)
          DescriptionPurified mouse monoclonal antibody. Recognizes the ~515 kDa LRP heavy chain protein.
          BackgroundInhibits the binding of LRP (Low Density Lipoprotein Receptor-Related Protein) to α2-macroglobulin. LRP contributes to the pathology of Alzheimer's disease by influencing both the production and clearance of the β-amyloid peptide.
          HostMouse
          Immunogen speciesHuman
          Immunogennative LRP from human placenta
          Clone8G1
          IsotypeIgG₁
          Specieshuman
          FormLiquid
          FormulationIn 100 mM NaCl, 50 mM phosphate buffer, pH 7.4.
          Concentration Label Please refer to vial label for lot-specific concentration
          PreservativeNone
          CommentsRecognizes the low density heavy chain (~515 kDa) by immunoblotting under non-reducing conditions. This antibody has also been reported to work for immunoprecipitation, flow cytometry, and ELISA. Variables associated with assay conditions will dictate the proper working dilution.
          Storage -20°C
          Avoid freeze/thaw
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Toxicity Standard Handling
          ReferencesMikhailenko, I., et al. 2001. J. Biol. Chem. 276, 39484.
          Rebeck, W.G., et al. 2001. Mol. Brain Res. 87, 238.
          Strickland, D.K., et al. 1990. J. Biol. Chem. 265, 17401.